Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MT-CO2 | P00403 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 2/20 | 0.34 |
| ▸ | DRD5 | P21918 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 4/20 | 0.33 |
| ▸ | CNR2 | P34972 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 4/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13985493 | 0.90 | CNR1 (0.35) | MT-CO2DRD1DRD5CNR1CNR2 | |
| SCHEMBL13985487 | 0.82 | OPRM1 (0.36) | DRD1DRD5CNR1CNR2MEN1 | |
| SCHEMBL13985416 | 0.79 | GPR119 (0.36) | — | |
| SCHEMBL4753709 | 0.78 | DRD1 (0.40) | DRD1DRD5KMT2ASMN1; SMN2AVPR1A | |
| SCHEMBL4753713 | 0.78 | DRD1 (0.40) | DRD1DRD5KMT2ASMN1; SMN2AVPR1A | |
| SCHEMBL4911234 | 0.73 | DRD1 (0.42) | DRD1DRD5KMT2ASMN1; SMN2AVPR1A | |
| SCHEMBL13985414 | 0.73 | DGAT1 (0.33) | — | |
| SCHEMBL13985298 | 0.73 | BRD4 (0.37) | CNR1CNR2MEN1KMT2ANPSR1 | |
| SCHEMBL4755753 | 0.72 | DRD1 (0.41) | DRD1DRD5KMT2ASMN1; SMN2AVPR1A | |
| SCHEMBL4755752 | 0.72 | DRD1 (0.41) | DRD1DRD5KMT2ASMN1; SMN2AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008156607-A1 | SUBSTITUTED PYRIMIDINONES | NEUROGEN CORPORATION (US) | 2008-12-24 | — | — | WO | disclosed |