Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.37 |
| ▸ | CDK7 | P50613 | 1/20 | 0.37 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | BAZ2B | Q9UIF8 | 3/20 | 0.35 |
| ▸ | BAZ2A | Q9UIF9 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3229293 | 0.84 | AKR1B1 (0.42) | L3MBTL1HTTATMKMT2AKDM4E | |
| SCHEMBL15491630 | 0.75 | ALDH1A1 (0.44) | MAP4K4ABL1MAPK8CSNK1A1CDK7 | |
| SCHEMBL17519485 | 0.71 | GGPS1 (0.54) | KMT2AKDM4ERAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6949233 | 0.71 | KDM4E (0.37) | L3MBTL1KMT2AKDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL6222799 | 0.70 | ALDH1A1 (0.34) | L3MBTL1KMT2AKDM4ERAB9AALDH1A1 | |
| SCHEMBL1722529 | 0.70 | PTGS2 (0.46) | HTTKMT2AKDM4EALDH1A1MEN1 | |
| SCHEMBL7073068 | 0.69 | TBXAS1 (0.44) | L3MBTL1HTTATMKMT2AKDM4E | |
| SCHEMBL8127371 | 0.68 | TBXAS1 (0.55) | L3MBTL1HTTATMKDM4ESMN1; SMN2 | |
| SCHEMBL6244092 | 0.68 | TBXAS1 (0.50) | MAPTCYP2D6 | |
| SCHEMBL5425400 | 0.68 | L3MBTL1 (0.37) | L3MBTL1HTTATMKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081306-A1 | INDOLIZINE COMPOUNDS FOR THE TREATMENT OF MENTAL DISORDERS OR MENTAL ENHANCEMENT | TACTOGEN INC (US) | 2023-05-11 | — | — | WO | disclosed |
| US-20080306109-A1 | Indolizine Derivatives as Ligands of the Crth2 Receptor | ARGENTA DISCOVERY LIMITED (GB) | 2008-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306109-A1 | Indolizine Derivatives as Ligands of the Crth2 Receptor | HRH4, HRH2, HRH3 | MAP4K4 4082/4885ABL1 3045/4885MAPK8 2624/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.