Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CETP | P11597 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14336221 | 0.89 | ALDH1A1 (0.46) | ALDH1A1GAAGFERHSP90AB1TNF | |
| SCHEMBL8144382 | 0.78 | ALDH1A1 (0.47) | ALDH1A1GAAGFERHSP90AB1KDM4E | |
| SCHEMBL13447477 | 0.76 | HSP90AB1 (0.48) | ALDH1A1GAAGFERHSP90AB1KDM4E | |
| SCHEMBL12877592 | 0.75 | ALDH1A1 (0.57) | ALDH1A1GAAGFERHSP90AB1TNF | |
| SCHEMBL502012 | 0.75 | ALDH1A1 (0.45) | ALDH1A1GAAGFERHSP90AB1KDM4E | |
| SCHEMBL13025363 | 0.75 | ALDH1A1 (0.45) | ALDH1A1GAAGFERHSP90AB1KDM4E | |
| SCHEMBL10272847 | 0.75 | CYP17A1 (0.41) | ALDH1A1GAAKDM4EGLA | |
| SCHEMBL23713473 | 0.74 | GAA (0.44) | ALDH1A1GAAGFERHSP90AB1KDM4E | |
| SCHEMBL9159002 | 0.74 | HSD17B10 (0.49) | ALDH1A1GAAGFERTNFKDM4E | |
| SCHEMBL2129842 | 0.73 | ALDH1A1 (0.50) | ALDH1A1GAAGFERHSP90AB1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080306179-A1 | Photopolymerizable compositions featuring novel amine accelerator for improved color stability and reduced polymerization stress thereby | DENTSPLY SIRONA INC. | 2008-12-11 | — | — | US | disclosed |