Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 1/20 | 0.36 |
| ▸ | ENPP1 | P22413 | 5/20 | 0.35 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 2/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.32 |
| ▸ | BCR | P11274 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.31 |
| ▸ | ACACA | Q13085 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13995120 | 0.96 | PTGS2 (0.38) | PTAFRENPP1ENPP3PTGS2DHODH | |
| SCHEMBL15453339 | 0.85 | PTAFR (0.42) | PTAFRENPP1ENPP3PTGS2KDM4E | |
| SCHEMBL13995118 | 0.84 | GPR84 (0.36) | ENPP1PTGS2DHODHKDM4EMEN1 | |
| SCHEMBL17739686 | 0.84 | ACHE (0.38) | PTAFRPTGS2KDM4EL3MBTL1MAPT | |
| SCHEMBL14445695 | 0.81 | ACHE (0.39) | PTAFRPTGS2KDM4EL3MBTL1MAPT | |
| SCHEMBL13162126 | 0.81 | HDAC4 (0.42) | KDM4EMEN1ALDH1A1KMT2AHSD17B10 | |
| SCHEMBL13995119 | 0.80 | GPR84 (0.38) | ENPP1KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL16263483 | 0.80 | ACHE (0.38) | ENPP1ENPP3PTGS2KDM4EL3MBTL1 | |
| SCHEMBL17739687 | 0.79 | ACHE (0.38) | PTAFRPTGS2KDM4EL3MBTL1MAPT | |
| SCHEMBL13162150 | 0.78 | ACHE (0.45) | PTGS2KDM4EL3MBTL1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8795847-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2014-08-05 | — | — | US | disclosed |
| US-20080303003-A1 | Novel Materials for Organic Electroluminescent Devices | MERCK PATENT GMBH (DE) | 2008-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080303003-A1 | Novel Materials for Organic Electroluminescent Devices | ANXA2, ANXA3, ANXA1 | PTAFR 4338/4885ENPP1 771/4885ENPP3 329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.