SCHEMBL17739686

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14445695	0.98	ACHE (0.39)	ACHEESR1ESR2KDM4EL3MBTL1
	SCHEMBL17739687	0.95	ACHE (0.38)	ACHEESR1ESR2KDM4EL3MBTL1
	SCHEMBL22180633	0.91	ACHE (0.44)	ACHEESR1ESR2KDM4EL3MBTL1
	SCHEMBL14195777	0.91	ACHE (0.36)	ACHEESR1ESR2KDM4EL3MBTL1
	SCHEMBL5948270	0.86	ACHE (0.41)	ACHEKDM4EL3MBTL1CYP1A2CYP3A4
	SCHEMBL6123492	0.86	ACHE (0.41)	ACHEKDM4EL3MBTL1CYP1A2CYP3A4
	SCHEMBL13995088	0.85	PLA2G2A (0.37)	ESR1L3MBTL1CYP3A4NR1H2NR1H3
	SCHEMBL13995124	0.84	PTAFR (0.36)	KDM4EL3MBTL1PTAFRMAPTPTGS2
	SCHEMBL24702946	0.83	TRIM58 (0.40)	ACHEESR1ESR2KDM4EL3MBTL1
	SCHEMBL5947814	0.83	ACHE (0.40)	ACHEKDM4EL3MBTL1CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.