SCHEMBL16263483

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13162150	0.89	ACHE (0.45)	ACHEESR1ESR2KDM4EMAPT
	SCHEMBL16805207	0.89	GPR84 (0.36)	ACHEENPP1GPR84ESR1ESR2
	SCHEMBL22180633	0.87	ACHE (0.44)	ACHEESR1ESR2KDM4EMAPT
	SCHEMBL14445695	0.85	ACHE (0.39)	ACHEESR1ESR2KDM4EMAPT
	SCHEMBL13995120	0.84	PTGS2 (0.38)	ENPP1GPR84KDM4EMAPTMAPK1
	SCHEMBL16805210	0.84	ENPP1 (0.36)	ACHEENPP1GPR84ESR1ESR2
	SCHEMBL26761796	0.84	ENPP1 (0.38)	ACHEENPP1GPR84ESR1ESR2
	SCHEMBL5948257	0.84	ACHE (0.36)	ACHEGPR84KDM4EMAPTTDP1
	SCHEMBL17739686	0.83	ACHE (0.38)	ACHEESR1ESR2KDM4EMAPT
	SCHEMBL17739687	0.83	ACHE (0.38)	ACHEESR1ESR2KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.