SCHEMBL139963

SCHEMBL139963

[CH2]c1ccc(O)c(OC)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.61
TRPA1 O75762 1/20 0.57
SLC22A6 Q4U2R8 1/20 0.53
SLC22A8 Q8TCC7 1/20 0.53
MEN1 O00255 1/20 0.53
RAB9A P51151 1/20 0.53
KMT2A Q03164 1/20 0.53
ALDH1A1 P00352 2/20 0.52
TRIM24 O15164 1/20 0.52
HPGD P15428 1/20 0.52
ALDH5A1 P51649 1/20 0.52
ABAT P80404 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
TRIM33 Q9UPN9 1/20 0.52
HTT P42858 1/20 0.52
CYP3A4 P08684 3/20 0.52
TSHR P16473 2/20 0.52
ALOX5 P09917 2/20 0.52
AR P10275 1/20 0.52
PTGS1 P23219 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL258124 0.82 ALDH1A1 (0.52) MEN1KMT2AALDH1A1CYP3A4TSHR
SCHEMBL27903152 0.80 CYP3A4 (0.51) MAOBRAB9AALDH1A1TDP1CYP3A4
SCHEMBL27090 0.78 CA2 (0.54) ALDH1A1HPGDTDP1CYP3A4TSHR
SCHEMBL258481 0.77 ALDH1A1 (0.56) MEN1KMT2AALDH1A1HPGDTDP1
SCHEMBL3693339 0.76 MAOB (0.67) MAOBTRPA1SLC22A6SLC22A8MEN1
SCHEMBL62784 0.76 MAOB (1.00) MAOBTRPA1SLC22A6SLC22A8MEN1
SCHEMBL29373807 0.76 MAOB (1.00) MAOBTRPA1SLC22A6SLC22A8MEN1
Formaldehyde SCHEMBL27695423 0.76 MAOB (0.87) MAOBTRPA1SLC22A6SLC22A8MEN1
SCHEMBL4386820 0.74 MAOB (0.64) MAOBTRPA1SLC22A6SLC22A8MEN1
Methoxymethane SCHEMBL10894687 0.74 MAOB (0.95) MAOBTRPA1SLC22A6SLC22A8MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2127 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4387587-A1 COMPOSITIONS Symrise AG (DE) 2024-06-26 EP claimed
WO-2024127352-A1 FORMULATION COMPRISING VANILLOID POLYPHENOLS SUPPORTED ON LAMELLAR SOLIDS TO REDUCE PLASMA CGRP LEVELS AND ITS APPLICATIONS PROLABIN & TEFARM S.R.L. (IT) 2024-06-20 WO claimed
EP-3444336-B1 CLEANING AGENT PROCTER & GAMBLE (US) 2024-05-08 EP claimed
CN-116590161-B Recombinant amycolatopsis for producing vanillin, construction method and application thereof 陕西海斯夫生物工程有限公司 2024-05-03 CN claimed
CN-117813077-A Composition and method for producing the same 西姆莱斯股份公司 2024-04-02 CN claimed
CN-115368523-B Multi-block thermoplastic elastomer and preparation method thereof 安徽农业大学 2024-03-19 CN claimed
CN-117645530-A RuNiZn/Nb 2 O 5 Method for depolymerizing lignin into phenolic compounds by catalyst 西安交通大学 2024-03-05 CN claimed
CN-117547059-A Reconstituted tobacco essential oil with Zimbabwe tobacco style, and preparation method and application thereof 江苏中烟工业有限责任公司 2024-02-13 CN claimed
WO-2024018436-A1 FLAVORED POROUS MATERIAL FOR FLAVORED BEVERAGE PRODUCTION LALLEMAND HUNGARY LIQUIDITY MANAGEMENT LLC (HU) 2024-01-25 WO claimed
CN-116837016-B Method for constructing recombinant escherichia coli engineering strain for producing capsaicin-vanilla nonanamide, recombinant strain and application 中国农业科学院北京畜牧兽医研究所 2024-01-02 CN claimed
EP-0941998-A2 3,6-ketal and enol ether macrolide antibiotics Pfizer Products Inc. (US) 1999-09-15 EP claimed
WO-1999003975-A1 IMPROVED VANILLIN PRODUCTION DAVID MICHAEL & CO., INC. (US) 1999-01-28 WO claimed
US-5721125-A Enzymatic process for producing 4-hydroxy-cinnamyl alcohols QUEST INTERNATIONAL B.V. (NL) 1998-02-24 US claimed
EP-0710289-B1 PROCESS FOR PRODUCING 4-HYDROXY-CINNAMYL ALCOHOLS QUEST INT (NL) 1997-02-12 EP claimed
US-5538018-A Cigarette smoking products containing a vanillin-release additive PHILIP MORRIS INCORPORATED (US) 1996-07-23 US claimed
EP-0710289-A1 PROCESS FOR PRODUCING 4-HYDROXY-CINNAMYL ALCOHOLS QUEST INT (NL) 1996-05-08 EP claimed
WO-1995002062-A1 PROCESS FOR PRODUCING 4-HYDROXY-CINNAMYL ALCOHOLS QUEST INTERNATIONAL B.V. (NL) 1995-01-19 WO claimed
WO-1993023061-A1 THERAPEUTIC USES OF PUNGENT BOTANICALS AND THEIR RELATED COMPOUNDS STAGGS JEFF J (US) 1993-11-25 WO claimed
US-4486179-A ESTERS OF SYRINGIC ACID AS ANTICARIES AGENTS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1984-12-04 US claimed
US-4134877-A Flame retardant phosphoramidate compositions MONSANTO COMPANY (US) 1979-01-16 US claimed