Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | TOP2A | P11388 | 1/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | BCR | P11274 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.45 |
| ▸ | ALPI | P09923 | 1/20 | 0.45 |
| ▸ | ALPG | P10696 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL309719 | 0.81 | KDM4E (0.46) | ALDH1A1KMT2AMEN1GAAMAPT | |
| SCHEMBL2319036 | 0.79 | ALDH1A1 (0.59) | ALDH1A1KMT2AMEN1TOP2AABL1 | |
| SCHEMBL4395020 | 0.79 | ALDH1A1 (0.59) | ALDH1A1KMT2AMEN1TOP2AABL1 | |
| SCHEMBL294390 | 0.78 | ALDH1A1 (0.58) | ALDH1A1KMT2AMEN1TOP2AABL1 | |
| SCHEMBL9353738 | 0.78 | MAPT (0.61) | ALDH1A1KMT2AMEN1TOP2AABL1 | |
| SCHEMBL8386278 | 0.78 | ALDH1A1 (0.58) | ALDH1A1KMT2AMEN1TOP2AABL1 | |
| SCHEMBL16962672 | 0.78 | ALDH1A1 (0.38) | ALDH1A1KMT2AMEN1GAAMAPT | |
| SCHEMBL15173354 | 0.77 | ALDH1A1 (0.54) | ALDH1A1KMT2AMEN1TOP2AABL1 | |
| SCHEMBL139963 | 0.77 | MAOB (0.61) | ALDH1A1KMT2AMEN1MAPTAR | |
| SCHEMBL356412 | 0.76 | KDM4E (0.59) | ALDH1A1KMT2AMEN1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3494104-B1 | WARMING SENSATION COMPOUNDS | TAKASAGO PERFUMERY CO LTD (JP) | 2023-11-15 | — | — | EP | claimed |
| JP-4722360-B2 | — | — | 2011-07-13 | — | — | JP | claimed |
| EP-1517880-B1 | PRODUCTION OF CIS-PELLITORIN AND USE AS A FLAVOURING | SYMRISE AG (DE) | 2011-01-05 | — | — | EP | claimed |
| EP-1278520-B1 | DIARYL PIPERIDYL PYRROLE DERIVATIVES AS ANTIPROTOZOAL AGENTS | MERCK & CO INC (US) | 2006-03-01 | — | — | EP | claimed |
| JP-2003527336-A | — | — | 2003-09-16 | — | — | JP | claimed |
| EP-1278520-A4 | DIARYL PIPERIDYL PYRROLE DERIVATIVES AS ANTIPROTOZOAL AGENTS | MERCK & CO INC (US) | 2003-05-02 | — | — | EP | claimed |
| EP-1278520-A1 | DIARYL PIPERIDYL PYRROLE DERIVATIVES AS ANTIPROTOZOAL AGENTS | Merck & Co., Inc. (US) | 2003-01-29 | — | — | EP | claimed |
| WO-2001034149-A1 | DIARYL PIPERIDYL PYRROLE DERIVATIVES AS ANTIPROTOZOAL AGENTS | MERCK & CO., INC. (US) | 2001-05-17 | — | — | WO | claimed |
| EP-2780326-B1 | METHOD FOR INHIBITION OF DEUBIQUITINATING ACTIVITY | VIVOLUX AB (SE) | 2018-12-26 | — | — | EP | disclosed |
| WO-2012154904-A1 | TROPOLONE COMPOUNDS FOR TREATING OR PREVENTING RETROVIRAL INFECTION | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2012-11-15 | — | — | WO | disclosed |
| US-8063107-B2 | Use of trans-pellitorin as flavor substance | SYMRISE AG (DE) | 2011-11-22 | — | — | US | disclosed |
| US-20100291005-A1 | USE OF TRANS-PELLITORIN AS FLAVOR SUBSTANCE | SYMRISE GMBH & CO. KG (DE) | 2010-11-18 | — | — | US | disclosed |
| US-7776923-B2 | Use of trans-pellitorin as flavor substance | SYMRISE GMBH & CO. KG (DE) | 2010-08-17 | — | — | US | disclosed |
| US-20100129515-A1 | FLAVOUR MODULATING SUBSTANCES | QUEST INTERNATIONAL SERVICES B.V. (NL) | 2010-05-27 | — | — | US | disclosed |
| US-20040241312-A1 | Use of 2E,4E-decadienoic acid isobutylamide for imparting a salivation inducing effect to a foodstuff, an oral hygiene preparation or a gourmet or snack preparation; preparation by amidating a dodecadienoate with isobutylamine | SYMRISE AG (DE) | 2004-12-02 | — | — | US | disclosed |
| EP-1278520-A4 | DIARYL PIPERIDYL PYRROLE DERIVATIVES AS ANTIPROTOZOAL AGENTS | MERCK & CO INC (US) | 2003-05-02 | — | — | EP | disclosed |
| EP-1278520-A1 | DIARYL PIPERIDYL PYRROLE DERIVATIVES AS ANTIPROTOZOAL AGENTS | Merck & Co., Inc. (US) | 2003-01-29 | — | — | EP | disclosed |
| US-6291480-B1 | CONTROL OF COCCIDIOSIS IN POULTRY. | MERCK & CO., INC. | 2001-09-18 | — | — | US | disclosed |
| WO-2001034149-A1 | DIARYL PIPERIDYL PYRROLE DERIVATIVES AS ANTIPROTOZOAL AGENTS | MERCK & CO., INC. (US) | 2001-05-17 | — | — | WO | disclosed |
| US-6043226-A | TREATING BACTERIAL, PARASITIC AND PROTOZOAL INFECTIONS | PFIZER INC. (US) | 2000-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100291005-A1 | USE OF TRANS-PELLITORIN AS FLAVOR SUBSTANCE | PTMA, TAS2R14, TAS2R16 | ALDH1A1 617/4885KMT2A 4057/4885MEN1 1950/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.