Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 7/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1399672 | 1.00 | ALDH1A1 (0.41) | ALDH1A1MAPTHPGDSMN1; SMN2PKM | |
| SCHEMBL1399740 | 0.90 | ALDH1A1 (0.39) | ALDH1A1MAPTHPGDSMN1; SMN2PKM | |
| SCHEMBL1399743 | 0.90 | ALDH1A1 (0.39) | ALDH1A1MAPTHPGDSMN1; SMN2PKM | |
| SCHEMBL1399630 | 0.90 | MAPT (0.38) | ALDH1A1MAPTHPGDSMN1; SMN2PKM | |
| SCHEMBL1399628 | 0.90 | MAPT (0.38) | ALDH1A1MAPTHPGDSMN1; SMN2PKM | |
| SCHEMBL3927315 | 0.86 | HCAR3 (0.39) | ALDH1A1MAPTHPGDSMN1; SMN2PKM | |
| SCHEMBL1399762 | 0.86 | DGAT1 (0.40) | ALDH1A1MAPTHPGDSMN1; SMN2PKM | |
| SCHEMBL1399760 | 0.86 | DGAT1 (0.40) | ALDH1A1MAPTHPGDSMN1; SMN2PKM | |
| SCHEMBL1399612 | 0.81 | MAPT (0.37) | ALDH1A1MAPTHPGDSMN1; SMN2PKM | |
| SCHEMBL1399610 | 0.81 | MAPT (0.37) | ALDH1A1MAPTHPGDSMN1; SMN2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2035417-B1 | BENZIMIDAZOLES AND THEIR USE FOR THE TREATEMNT OF DIABETES | ASTRAZENECA AB (SE) | 2011-03-02 | — | — | EP | disclosed |
| US-20090197926-A1 | BENZIMIDAZOLES AND THEIR USE FOR THE TREATMENT OF DIABETES | ASTRAZENECA AB (SE) | 2009-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090197926-A1 | BENZIMIDAZOLES AND THEIR USE FOR THE TREATMENT OF DIABETES | DGAT1, ACAT1, DGAT2 | ALDH1A1 112/4885MAPT 2285/4885HPGD 1301/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.