Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | CASP3 | P42574 | 2/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17485426 | 0.85 | NPC1 (0.35) | NPC1RAB9ASMN1; SMN2KMT2AHTT | |
| SCHEMBL17485425 | 0.84 | RAB9A (0.39) | NPC1RAB9ASMN1; SMN2KMT2AHTT | |
| SCHEMBL26024103 | 0.82 | HTT (0.35) | NPC1RAB9ASMN1; SMN2KMT2AHTT | |
| SCHEMBL29867943 | 0.77 | CASP3 (0.32) | NPC1RAB9ASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL7736866 | 0.77 | CASP3 (0.32) | NPC1RAB9ASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL22650959 | 0.76 | NPC1 (0.36) | NPC1RAB9ASMN1; SMN2KMT2AHTT | |
| SCHEMBL23084630 | 0.74 | NPC1 (0.35) | NPC1RAB9ASMN1; SMN2KMT2AHTT | |
| SCHEMBL20712022 | 0.74 | CASP3 (0.32) | NPC1RAB9ASMN1; SMN2KMT2AHTT | |
| SCHEMBL21155600 | 0.73 | KMT2A (0.36) | SMN1; SMN2KMT2AALDH1A1L3MBTL1LMNA | |
| SCHEMBL23698705 | 0.73 | ALDH1A1 (0.35) | NPC1RAB9ASMN1; SMN2KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7459561-B2 | N-substituted carbamoyloxyalkyl-azolium derivatives | BASILEA PHARMACEUTICA AG (CH) | 2008-12-02 | — | — | US | disclosed |