Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | CXCR1 | P25024 | 3/20 | 0.39 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | PTH1R | Q03431 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24196455 | 0.81 | FAAH (0.46) | EPHX1MAPTSMN1; SMN2GAACRHBP | |
| SCHEMBL27421353 | 0.79 | SMN1; SMN2 (0.41) | MAPTSMN1; SMN2GAACRHBPCRHR2 | |
| SCHEMBL20715472 | 0.78 | ABL1 (0.44) | EPHX1MAPTSMN1; SMN2GAACRHBP | |
| SCHEMBL26769169 | 0.78 | ALDH1A1 (0.50) | EPHX1MAPTSMN1; SMN2GAACRHBP | |
| SCHEMBL12298580 | 0.78 | MAPT (0.42) | EPHX1MAPTSMN1; SMN2GAACRHBP | |
| SCHEMBL10810619 | 0.78 | TAAR1 (0.52) | MAPTGAAALDH1A1LMNABLM | |
| SCHEMBL26648429 | 0.77 | ITGB3 (0.46) | MEN1KMT2A | |
| SCHEMBL9320348 | 0.77 | MAPT (0.41) | MAPTSMN1; SMN2GAAALDH1A1LMNA | |
| SCHEMBL28134712 | 0.77 | LOXL2 (0.48) | MAPTALDH1A1CA12CA4CA9 | |
| SCHEMBL4409856 | 0.76 | STK17B (0.43) | EPHX1MAPTSMN1; SMN2GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080293711-A1 | Chemokine receptor modulators | METASTATIX, INC. | 2008-11-27 | — | — | US | disclosed |
| US-20080293711-A1 | Chemokine receptor modulators | METASTATIX, INC. | 2008-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293711-A1 | Chemokine receptor modulators | CCR5, CCL2, CXCR4 | EPHX1 770/4885MAPT 4253/4885SMN1; SMN2 4829/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.