SCHEMBL14005285

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4896185	0.84	HRH4 (0.75)	HRH4PIK3CBMETTL3CASP1CASP5
	SCHEMBL4894189	0.83	HRH4 (0.53)	HRH4PIK3CBPRCPKDM4EALDH1A1
	SCHEMBL8681808	0.75	HRH4 (0.73)	HRH4DRD2DRD3DRD4
	SCHEMBL5029686	0.73	PIK3CB (0.80)	HRH4PIK3CBMETTL3PRCPHTT
	SCHEMBL23964222	0.72	DRD4 (0.60)	HRH4KDM4EALDH1A1MAPTDRD2
	SCHEMBL4896683	0.72	HRH4 (0.51)	HRH4PIK3CBCASP1CASP5HTT
	SCHEMBL8683849	0.71	HRH3 (0.72)	HRH4DRD2DRD3
	SCHEMBL14070642	0.71	HRH4 (0.50)	HRH4PIK3CBMETTL3CASP1CASP5
	SCHEMBL4787976	0.70	HTR7 (0.53)	HRH4PIK3CBMETTL3CASP1CASP5
	SCHEMBL4888066	0.70	HTR7 (0.53)	HRH4PIK3CBMETTL3CASP1CASP5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.