Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CB | P42338 | 3/20 | 0.80 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.80 |
| ▸ | ACHE | P22303 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.50 |
| ▸ | PRCP | P42785 | 2/20 | 0.50 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5029684 | 0.89 | PIK3CB (1.00) | PIK3CBHRH4ACHEALDH1A1HTT | |
| SCHEMBL4896185 | 0.88 | HRH4 (0.75) | PIK3CBHRH4ACHECYP1A2CYP2D6 | |
| SCHEMBL14005278 | 0.82 | HRH4 (0.73) | PIK3CBHRH4ACHECYP1A2CYP2D6 | |
| SCHEMBL1774199 | 0.81 | HRH4 (0.66) | PIK3CBHRH4SMN1; SMN2CYP1A2CYP2D6 | |
| SCHEMBL14005277 | 0.81 | HRH4 (0.65) | PIK3CBHRH4ACHESMN1; SMN2CYP1A2 | |
| SCHEMBL8798290 | 0.79 | SMN1; SMN2 (0.59) | PIK3CBHRH4SMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL31660945 | 0.78 | SMN1; SMN2 (0.61) | PIK3CBHRH4SMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL15721555 | 0.77 | ACHE (0.64) | PIK3CBHRH4ACHECYP1A2CYP2D6 | |
| SCHEMBL6244393 | 0.76 | HRH4 (0.60) | PIK3CBHRH4ACHESMN1; SMN2CYP1A2 | |
| SCHEMBL3231445 | 0.75 | MMP13 (0.67) | PIK3CBHRH4SMN1; SMN2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101438288-A | Regulation of phosphoryl transferase activity of glutamine synthetase | CSIR CORP (ZA) | 2009-05-20 | — | — | CN | disclosed |
| EP-2008210-A1 | MODULATION OF PHOSPHORYL TRANSFERASE ACTIVITY OF GLUTAMINE SYNTHETASE | CSIR (ZA) | 2008-12-31 | — | — | EP | disclosed |
| WO-2007105023-A1 | MODULATION OF PHOSPHORYL TRANSFERASE ACTIVITY OF GLUTAMINE SYNTHETASE | CSIR (ZA) | 2007-09-20 | — | — | WO | disclosed |
| WO-2007105023-A1 | MODULATION OF PHOSPHORYL TRANSFERASE ACTIVITY OF GLUTAMINE SYNTHETASE | CSIR (ZA) | 2007-09-20 | — | — | WO | disclosed |