Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.53 |
| ▸ | DRD4 | P21917 | 13/20 | 0.53 |
| ▸ | DRD2 | P14416 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.51 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | PRCP | P42785 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14005279 | 0.84 | DRD4 (0.48) | HRH4DRD4DRD2KDM4EALDH1A1 | |
| SCHEMBL14005285 | 0.83 | HRH4 (0.54) | HRH4DRD4DRD2KDM4EALDH1A1 | |
| SCHEMBL14005284 | 0.83 | DRD4 (0.50) | DRD4DRD2KDM4EALDH1A1CYP3A4 | |
| SCHEMBL4896185 | 0.83 | HRH4 (0.75) | HRH4KDM4ECYP3A4ALOX15PIK3CB | |
| SCHEMBL5626446 | 0.76 | DRD4 (0.74) | DRD4DRD2KDM4EALDH1A1CYP3A4 | |
| SCHEMBL4436381 | 0.73 | BCHE (0.61) | DRD4DRD2KDM4EALDH1A1NPC1 | |
| SCHEMBL9202923 | 0.72 | HTT (0.76) | DRD4DRD2KDM4EALDH1A1CYP3A4 | |
| SCHEMBL5029686 | 0.72 | PIK3CB (0.80) | HRH4ALDH1A1CYP3A4ALOX15PIK3CB | |
| SCHEMBL25505695 | 0.72 | DRD4 (0.63) | DRD4DRD2KDM4EALDH1A1CYP3A4 | |
| SCHEMBL4896683 | 0.71 | HRH4 (0.51) | HRH4DRD4KDM4ESIGMAR1PIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080293711-A1 | Chemokine receptor modulators | METASTATIX, INC. | 2008-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293711-A1 | Chemokine receptor modulators | CCR5, CCL2, CXCR4 | HRH4 1565/4885DRD4 4184/4885DRD2 4070/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.