Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | CXCR3 | P49682 | 10/20 | 0.59 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14005305 | 0.88 | ALDH1A1 (0.50) | KMT2ACXCR3KCNA5HDAC3HDAC11 | |
| SCHEMBL14004928 | 0.82 | PTGS2 (0.49) | CXCR3HDAC3HDAC11HDAC8HDAC6 | |
| SCHEMBL4744575 | 0.80 | L3MBTL1 (0.48) | KMT2AHDAC3HDAC6MAPTSMN1; SMN2 | |
| SCHEMBL14004929 | 0.80 | ESR1 (0.51) | KMT2AHDAC3HDAC11HDAC8HDAC6 | |
| SCHEMBL12863694 | 0.79 | CXCR3 (0.75) | KMT2ACXCR3KCNA5TAS2R14 | |
| SCHEMBL14005299 | 0.78 | L3MBTL1 (0.44) | KMT2AHDAC3HDAC11HDAC8HDAC6 | |
| SCHEMBL9362917 | 0.78 | KMT2A (1.00) | KMT2ACXCR3KCNA5MAPTSMN1; SMN2 | |
| SCHEMBL1169383 | 0.78 | CXCR3 (0.78) | KMT2ACXCR3KCNA5TAS2R14 | |
| SCHEMBL1169939 | 0.77 | CXCR3 (0.71) | KMT2ACXCR3KCNA5HDAC3HDAC11 | |
| SCHEMBL1169755 | 0.77 | CXCR3 (0.69) | KMT2ACXCR3KCNA5TAS2R14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080293711-A1 | Chemokine receptor modulators | METASTATIX, INC. | 2008-11-27 | — | — | US | disclosed |
| US-20080293711-A1 | Chemokine receptor modulators | METASTATIX, INC. | 2008-11-27 | — | — | US | disclosed |
| WO-2008112156-A1 | CHEMOKINE RECEPTOR MODULATORS | ALTIRIS THERAPEUTICS (US) | 2008-09-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293711-A1 | Chemokine receptor modulators | CCR5, CCL2, CXCR4 | KMT2A 4463/4885CXCR3 5/4885KCNA5 4394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.