Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6686729 | 0.88 | NTRK1 (0.58) | KDM4EGAANTRK1SLC2A1CYP1A2 | |
| SCHEMBL8208 | 0.79 | KDM4E (0.64) | KDM4EGAASLC2A1SMN1; SMN2NPC1 | |
| SCHEMBL14005645 | 0.78 | MAPK1 (0.48) | MAPK1KDM4EGAANTRK1CYP1A2 | |
| SCHEMBL13341895 | 0.77 | NPC1 (0.56) | KDM4EGAANTRK1SLC2A1CYP1A2 | |
| SCHEMBL13341887 | 0.77 | SMN1; SMN2 (0.56) | KDM4ENTRK1SLC2A1CYP1A2CYP2C9 | |
| SCHEMBL7096969 | 0.77 | NTRK1 (0.56) | KDM4EGAANTRK1SLC2A1CYP1A2 | |
| SCHEMBL22780401 | 0.75 | NTRK1 (0.57) | KDM4EGAANTRK1SLC2A1CYP1A2 | |
| SCHEMBL13341897 | 0.74 | GABRB2 (0.62) | KDM4ECYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL13341900 | 0.74 | ALDH1A1 (0.61) | KDM4ENTRK1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL1730262 | 0.73 | MARK4 (0.52) | MAPK1KDM4EGAANTRK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080293947-A1 | Method of Preparation for Imidazolepyridines | MALLINCKRODT INC. | 2008-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293947-A1 | Method of Preparation for Imidazolepyridines | ITPA, QDPR, NISCH | MAPK1 2042/4885KDM4E 1146/4885GAA 2565/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.