Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.59 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.59 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | TTR | P02766 | 1/20 | 0.54 |
| ▸ | PPOX | P50336 | 1/20 | 0.54 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.53 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29446908 | 1.00 | TDP1 (0.59) | TDP1ALDH1A1TSHRCYP3A4HPGD | |
| SCHEMBL140068 | 0.85 | ALDH1A1 (0.65) | TDP1ALDH1A1TSHRCYP3A4HPGD | |
| SCHEMBL10706908 | 0.84 | TDP1 (0.74) | TDP1ALDH1A1TSHRCYP3A4HPGD | |
| SCHEMBL3480508 | 0.84 | TDP1 (0.54) | TDP1ALDH1A1TSHRCYP3A4HPGD | |
| SCHEMBL5179497 | 0.83 | TSHR (0.60) | TDP1ALDH1A1TSHRCYP3A4HPGD | |
| SCHEMBL7240751 | 0.82 | ALDH1A1 (0.60) | TDP1ALDH1A1TSHRCYP3A4HPGD | |
| SCHEMBL29942185 | 0.82 | ALDH1A1 (0.60) | TDP1ALDH1A1TSHRCYP3A4HPGD | |
| Nitric Acid SCHEMBL11801207 | 0.81 | ALDH1A1 (0.59) | TDP1ALDH1A1TSHRCYP3A4HPGD | |
| Nitric Acid SCHEMBL11801208 | 0.81 | ALDH1A1 (0.59) | TDP1ALDH1A1TSHRCYP3A4HPGD | |
| SCHEMBL10769585 | 0.80 | TDP1 (0.60) | TDP1ALDH1A1TSHRCYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 140 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115991873-A | Low-dielectric fluorinated aromatic polyimide film and preparation method thereof | 慧创(东莞)材料技术有限责任公司 | 2023-04-21 | — | — | CN | claimed |
| US-12351559-B2 | Benzoimidazol benzomidazol-1,2-yl amides as Kv7 channel activators | BIOHAVEN THERAPEUTICS LTD. (VG) | 2025-07-08 | — | — | US | disclosed |
| EP-4543863-A1 | FERROPTOSIS INHIBITORS AND USES THEREOF | University Of Ottawa (CA) | 2025-04-30 | — | — | EP | disclosed |
| WO-2025045835-A1 | PESTICIDALLY ACTIVE OXOINDOLE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2025-03-06 | — | — | WO | disclosed |
| US-12187723-B2 | Substituted benzimidazolone compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-01-07 | — | — | US | disclosed |
| US-20240300903-A1 | BENZOMIDAZOL-1,2-YL AMDES AS Kv7 CHANNEL ACTIVATORS | BIOHAVEN THERAPEUTICS LTD (US) | 2024-09-12 | — | — | US | disclosed |
| US-20240279205-A1 | NOVEL BENZIMIDAZOLE DERIVATIVE | CARNA BIOSCIENCES, INC. (JP) | 2024-08-22 | — | — | US | disclosed |
| EP-3965888-B1 | SUBSTITUTED BENZIMIDAZOLONE COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2024-08-21 | — | — | EP | disclosed |
| EP-3860994-B1 | TRANSCRIPTION FACTOR BRN2 INHIBITORY COMPOUNDS AS THERAPEUTICS AND METHODS FOR THEIR USE | UNIV BRITISH COLUMBIA (CA) | 2024-08-14 | — | — | EP | disclosed |
| WO-2023245297-A1 | FERROPTOSIS INHIBITORS AND USES THEREOF | UNIVERSITY OF OTTAWA (CA) | 2023-12-28 | — | — | WO | disclosed |
| EP-0536419-A1 | TRICYCLIC TRIAZOLE DERIVATIVE, PRODUCTION THEREOF, AND USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 1993-04-14 | — | — | EP | disclosed |
| US-4786739-A | SULFIDING | E. I. DUPONT DE NEMOURS AND COMPANY (US) | 1988-11-22 | — | — | US | disclosed |
| EP-0146610-A4 | SUBSTITUTED BENZOPENTATHIEPINS, PROCESS THEREFOR AND INTERMEDIATES. | DU PONT (US) | 1986-02-20 | — | — | EP | disclosed |
| US-4571404-A | PLANT HERBICIDE, FUNGICIDE OR VIRICIDE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-02-18 | — | — | US | disclosed |
| EP-0146610-A1 | SUBSTITUTED BENZOPENTATHIEPINS, PROCESS THEREFOR AND INTERMEDIATES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-07-03 | — | — | EP | disclosed |
| WO-1984004921-A1 | SUBSTITUTED BENZOPENTATHIEPINS, PROCESS THEREFOR AND INTERMEDIATES | DU PONT (US) | 1984-12-20 | — | — | WO | disclosed |
| US-4224340-A | Anti-inflammatory compositions containing α-phenyl-N-phenylnitrone compounds | WILLIAM H. RORER, INC. (US) | 1980-09-23 | — | — | US | disclosed |
| US-4214003-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1980-07-22 | — | — | US | disclosed |
| US-4197314-A | WITH A DIPHENYL NITRONE | WILLIAM H. RORER, INC. (US) | 1980-04-08 | — | — | US | disclosed |
| US-4153722-A | ANTIINFLAMMATORY, A-PHENYL-N-PHENYLNITRONE | WILLIAM H. RORER, INC. (US) | 1979-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12187723-B2 | Substituted benzimidazolone compounds | TLR7, TLR1, TLR9 | TDP1 1768/4885ALDH1A1 988/4885TSHR 1227/4885 |
| US-20240300903-A1 | BENZOMIDAZOL-1,2-YL AMDES AS Kv7 CHANNEL ACTIVATORS | KCNA7, KCNK17, KCNK2 | TDP1 2109/4885ALDH1A1 1492/4885TSHR 3468/4885 |
| US-20240279205-A1 | NOVEL BENZIMIDAZOLE DERIVATIVE | STING1, IRF3, TBK1 | TDP1 414/4885ALDH1A1 2046/4885TSHR 3190/4885 |
| US-12351559-B2 | Benzoimidazol benzomidazol-1,2-yl amides as Kv7 channel activators | KCNA7, KCNJ2, KCNK17 | TDP1 2705/4885ALDH1A1 2065/4885TSHR 3903/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.