Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.53 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.53 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | VCAM1 | P19320 | 6/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | XBP1 | P17861 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | DHFR | P00374 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL140068 | 0.86 | ALDH1A1 (0.65) | ALDH1A1TDP1CYP3A4HPGDALOX15 | |
| SCHEMBL2461199 | 0.86 | VCAM1 (0.58) | ALDH1A1TDP1TSHRMAPTMEN1 | |
| SCHEMBL5992360 | 0.84 | VCAM1 (0.60) | ALDH1A1TDP1TSHRMAPTMEN1 | |
| Nitric Acid SCHEMBL11801207 | 0.82 | ALDH1A1 (0.59) | ALDH1A1TDP1CYP3A4HPGDALOX15 | |
| Nitric Acid SCHEMBL11801208 | 0.82 | ALDH1A1 (0.59) | ALDH1A1TDP1CYP3A4HPGDALOX15 | |
| SCHEMBL3901007 | 0.81 | TDP1 (0.71) | ALDH1A1TDP1CYP3A4HPGDALOX15 | |
| SCHEMBL31009481 | 0.80 | MEN1 (0.53) | ALDH1A1TDP1CYP3A4HPGDALOX15 | |
| SCHEMBL3900786 | 0.80 | TDP1 (0.55) | ALDH1A1TDP1CYP3A4HPGDALOX15 | |
| SCHEMBL10663504 | 0.80 | MAPT (0.66) | ALDH1A1MAPTMEN1KMT2AVCAM1 | |
| SCHEMBL1897629 | 0.80 | CRHBP (0.58) | ALDH1A1TDP1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5728881-A | Process for preparing trifluralin | SRM CHEMICAL, LTD. CO. (US) | 1998-03-17 | — | — | US | disclosed |