Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC1 | P07992 | 2/20 | 0.48 |
| ▸ | ERCC4 | Q92889 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | SNCA | P37840 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TOP1 | P11387 | 1/20 | 0.41 |
| ▸ | PYGL | P06737 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14012049 | 0.83 | POLB (0.43) | GAAPKMCA12CA1CA2 | |
| SCHEMBL14012044 | 0.81 | MAOA (0.52) | GAASMN1; SMN2CA12CA1CA2 | |
| SCHEMBL3347728 | 0.79 | EPHX1 (0.64) | GAASMN1; SMN2CA2CA9KMT2A | |
| SCHEMBL14012045 | 0.79 | ALDH1A1 (0.56) | SMN1; SMN2CA12CA1CA2CA9 | |
| SCHEMBL14423988 | 0.79 | MAPT (0.60) | ERCC1ERCC4ALOX15KMT2AMEN1 | |
| SCHEMBL109020 | 0.78 | ALOX15 (0.66) | ERCC1ERCC4ALOX15PKMSNCA | |
| SCHEMBL14012042 | 0.76 | NPC1 (0.58) | SMN1; SMN2KMT2AMEN1HTTALDH1A1 | |
| SCHEMBL9673117 | 0.75 | ALOX15 (0.54) | ERCC1ERCC4ALOX15GAASNCA | |
| SCHEMBL13804531 | 0.75 | ALDH1A1 (0.55) | ERCC1ERCC4ALOX15PKMSMN1; SMN2 | |
| SCHEMBL108218 | 0.75 | ERCC1 (0.78) | ERCC1ERCC4SMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8809527-B2 | Modulators of toll-like receptors | GILEAD SCIENCES, INC. (US) | 2014-08-19 | — | — | US | disclosed |
| US-7456132-B2 | Phenol compound, reversible thermosensitive recording medium, reversible thermosensitive recording label, reversible thermosensitive recording member, image-processing apparatus and imaging-processing method | RICOH COMPANY, LTD. (JP) | 2008-11-25 | — | — | US | disclosed |
| US-20070225161-A1 | Phenol Compound, Reversible Thermosensitive Recording Medium, Reversible Thermosensitive Recording Label, Reversible Thermosensitive Recording Member, Image-Processing Apparatus and Imaging-Processing Method | RICOH COMPANY, LTD. (JP) | 2007-09-27 | — | — | US | disclosed |