Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 7/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 5/20 | 0.36 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.36 |
| ▸ | CPB1 | P15086 | 1/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.36 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11964062 | 0.84 | AKT1 (0.42) | AKT1SIRT1CA1CA2SIRT2 | |
| SCHEMBL10026185 | 0.84 | AKT1 (0.39) | AKT1SIRT1EPHX1CA1CA2 | |
| SCHEMBL14755924 | 0.82 | AKT1 (0.41) | AKT1SIRT1CA1CA2SIRT2 | |
| SCHEMBL4761500 | 0.82 | SIRT6 (0.48) | SIRT1CA1CA2SIRT6 | |
| SCHEMBL327667 | 0.81 | SIRT1 (0.36) | AKT1SIRT1EPHX1CA1CA2 | |
| SCHEMBL10167189 | 0.80 | AKT1 (0.37) | AKT1SIRT1EPHX1SIRT2 | |
| SCHEMBL11964063 | 0.80 | SIRT2 (0.38) | AKT1SIRT1CA1CA2SIRT2 | |
| SCHEMBL12415421 | 0.78 | SIRT1 (0.34) | SIRT1EPHX1CA1CA2SIRT2 | |
| SCHEMBL14542727 | 0.78 | AKT1 (0.36) | AKT1SIRT1SIRT2 | |
| SCHEMBL825245 | 0.78 | EPHX1 (0.39) | AKT1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7432331-B2 | Hydrolytically stable maleimide-terminated polymers | NEKTAR THERAPEUTICS AL, CORPORATION (US) | 2008-10-07 | — | — | US | disclosed |
| US-7432330-B2 | Hydrolytically stable maleimide-terminated polymers | NEKTAR THERAPEUTICS AL, CORPORATION (US) | 2008-10-07 | — | — | US | disclosed |