Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.43 |
| ▸ | MASP2 | O00187 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14016799 | 0.90 | ALDH1A1 (0.48) | LMNAALDH1A1SMN1; SMN2MAPK1RAB9A | |
| SCHEMBL14016781 | 0.87 | ALDH1A1 (0.48) | LMNAALDH1A1SMN1; SMN2MAPK1RAB9A | |
| SCHEMBL14016794 | 0.85 | ALDH1A1 (0.48) | LMNAALDH1A1SMN1; SMN2MAPK1RAB9A | |
| SCHEMBL14016785 | 0.82 | MEN1 (0.46) | LMNAALDH1A1SMN1; SMN2MAPK1RAB9A | |
| SCHEMBL6156837 | 0.78 | SCN2A (0.57) | ALDH1A1NR1H3KMT2AMEN1CASP6 | |
| SCHEMBL11304554 | 0.76 | L3MBTL1 (0.74) | LMNAALDH1A1SMN1; SMN2MAPK1RECQL | |
| SCHEMBL30758606 | 0.76 | RECQL (0.62) | LMNAALDH1A1SMN1; SMN2MAPK1RECQL | |
| SCHEMBL16592564 | 0.76 | RECQL (0.62) | LMNAALDH1A1SMN1; SMN2MAPK1RECQL | |
| SCHEMBL6153332 | 0.75 | AR (0.46) | ALDH1A1NR1H3KMT2AMEN1CASP6 | |
| SCHEMBL18806465 | 0.73 | RECQL (0.62) | LMNAALDH1A1RECQLL3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050182040-A1 | Benzamide derivatives | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2005-08-18 | — | — | US | disclosed |
| EP-1500643-A1 | BENZAMIDE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2005-01-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050182040-A1 | Benzamide derivatives | ROCK1, ROCK2, NHERF1 | LMNA 1200/4885ALDH1A1 2454/4885SMN1; SMN2 3598/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.