Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.30 |
| ▸ | PTAFR | P25105 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4851091 | 0.89 | DNM1 (0.37) | TDP1KDM4EL3MBTL1 | |
| SCHEMBL14018852 | 0.89 | DNM1 (0.37) | TDP1KDM4EL3MBTL1 | |
| SCHEMBL4851098 | 0.89 | DNM1 (0.37) | TDP1KDM4EL3MBTL1 | |
| SCHEMBL14017688 | 0.77 | DNM1 (0.39) | TDP1L3MBTL1 | |
| SCHEMBL14488715 | 0.75 | CES2 (0.34) | TDP1KDM4ETBXAS1MTNR1AMTNR1B | |
| SCHEMBL6049371 | 0.74 | TDP1 (0.62) | TDP1L3MBTL1 | |
| SCHEMBL2806471 | 0.74 | LMNA (0.40) | TDP1KDM4EL3MBTL1 | |
| SCHEMBL2806467 | 0.74 | LMNA (0.40) | TDP1KDM4EL3MBTL1 | |
| SCHEMBL14379637 | 0.74 | TDP1 (0.45) | TDP1L3MBTL1 | |
| SCHEMBL14379706 | 0.73 | TDP1 (0.39) | TDP1KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7439380-B2 | Diarylbutadiene-substituted diorganopolysiloxanes and photoprotective compositions comprised thereof | L'OREAL (FR) | 2008-10-21 | — | — | US | disclosed |
| US-7229610-B2 | Diarylbutadiene-substituted diorganopolysiloxanes and photoprotective compositions comprised thereof | L'OREAL (FR) | 2007-06-12 | — | — | US | disclosed |