Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
| ▸ | PRKCA | P17252 | 1/20 | 0.45 |
| ▸ | AKT1 | P31749 | 1/20 | 0.45 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.45 |
| ▸ | NT5E | P21589 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 8/20 | 0.43 |
| ▸ | CA1 | P00915 | 8/20 | 0.43 |
| ▸ | CA2 | P00918 | 8/20 | 0.43 |
| ▸ | CA9 | Q16790 | 8/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21134972 | 0.88 | TSHR (0.50) | LMNACYP2D6MAPK1KMT2ATSHR | |
| SCHEMBL22677782 | 0.87 | NT5E (0.49) | NT5E | |
| SCHEMBL12920540 | 0.86 | NT5E (0.50) | LMNACYP2D6ALDH1A1MAPK1KMT2A | |
| SCHEMBL17501955 | 0.85 | LMNA (0.58) | LMNACYP2D6ALDH1A1MAPK1KMT2A | |
| SCHEMBL17501966 | 0.85 | LMNA (0.58) | LMNACYP2D6ALDH1A1MAPK1KMT2A | |
| SCHEMBL17501962 | 0.85 | LMNA (0.58) | LMNACYP2D6ALDH1A1MAPK1KMT2A | |
| SCHEMBL17501958 | 0.85 | LMNA (0.58) | LMNACYP2D6ALDH1A1MAPK1KMT2A | |
| SCHEMBL24086068 | 0.83 | LMNA (0.63) | LMNACYP2D6ALDH1A1MAPK1KMT2A | |
| SCHEMBL17502040 | 0.83 | LMNA (0.63) | LMNACYP2D6ALDH1A1MAPK1KMT2A | |
| SCHEMBL970376 | 0.83 | LMNA (0.63) | LMNACYP2D6ALDH1A1MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080249165-A1 | Glycosides and Salts Thereof | IVAX DRUG RESEARCH INSTITUTE LTD. (HU) | 2008-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249165-A1 | Glycosides and Salts Thereof | AREG, MRGPRX2, IL33 | LMNA 4117/4885CYP2D6 2165/4885ALDH1A1 1484/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.