Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | PRKCA | P17252 | 1/20 | 0.47 |
| ▸ | AKT1 | P31749 | 1/20 | 0.47 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.47 |
| ▸ | ANTXR2 | P58335 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.44 |
| ▸ | PDE5A | O76074 | 1/20 | 0.44 |
| ▸ | HMGCR | P04035 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2528448 | 0.89 | PTPN1 (0.53) | TSHRPTPN1PAX8ANTXR2USP2 | |
| SCHEMBL7617205 | 0.89 | PTPN1 (0.53) | TSHRPTPN1PAX8ANTXR2USP2 | |
| SCHEMBL2522369 | 0.89 | PTPN1 (0.53) | TSHRPTPN1PAX8ANTXR2USP2 | |
| SCHEMBL14020069 | 0.88 | LMNA (0.48) | TSHRPAX8PRKCAAKT1PTK2 | |
| SCHEMBL14199417 | 0.87 | TSHR (0.47) | TSHRPTPN1PAX8PRKCAAKT1 | |
| SCHEMBL23266725 | 0.87 | PTPN1 (0.57) | TSHRPTPN1PAX8ANTXR2USP2 | |
| SCHEMBL15344765 | 0.86 | PAX8 (0.46) | TSHRPTPN1PAX8PRKCAAKT1 | |
| SCHEMBL23266721 | 0.86 | PTPN1 (0.50) | TSHRPTPN1PAX8PRKCAAKT1 | |
| SCHEMBL13290315 | 0.86 | PTPN1 (0.46) | PTPN1ANTXR2USP2KMT2AMEN1 | |
| SCHEMBL17779864 | 0.86 | PTPN1 (0.46) | PTPN1ANTXR2USP2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210009620-A1 | PURE HEPTASULFATED DISACCHARIDES HAVING IMPROVED ORAL BIOAVAILABILITY | OPKO PHARMACEUTICALS, LLC. | 2021-01-14 | — | — | US | disclosed |
| US-10829509-B2 | Pure heptasulfated disaccharides having improved oral bioavailability | OPKO PHARMACEUTICALS, LLC (US) | 2020-11-10 | — | — | US | disclosed |
| US-20190185503-A1 | PURE HEPTASULFATED DISACCHARIDES HAVING IMPROVED ORAL BIOAVAILABILITY | OPKO PHARMACEUTICALS, LLC. | 2019-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210009620-A1 | PURE HEPTASULFATED DISACCHARIDES HAVING IMPROVED ORAL BIOAVAILABILITY | SI, GYS1, UGGT1 | TSHR 3796/4885PTPN1 2380/4885PAX8 3828/4885 |
| US-10829509-B2 | Pure heptasulfated disaccharides having improved oral bioavailability | SI, GYS1, UGGT1 | TSHR 3796/4885PTPN1 2380/4885PAX8 3828/4885 |
| US-20190185503-A1 | PURE HEPTASULFATED DISACCHARIDES HAVING IMPROVED ORAL BIOAVAILABILITY | SI, GYS1, UGGT1 | TSHR 3796/4885PTPN1 2380/4885PAX8 3828/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.