SCHEMBL1402224

SCHEMBL1402224

CCN1CCCC1N(C)C(=O)C(C)n1c(C)c(NC=O)c(C)c1C=O

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1402225 0.84
SCHEMBL1313252 0.79 L3MBTL1 (0.46) L3MBTL1
SCHEMBL1313249 0.70 TSHR (0.33) L3MBTL1
SCHEMBL1313276 0.69 ACKR3 (0.37)
SCHEMBL1312421 0.69 DRD2 (0.35) L3MBTL1
SCHEMBL1312314 0.67 ALDH1A1 (0.44) L3MBTL1
SCHEMBL1313254 0.64 L3MBTL1 (0.47) L3MBTL1
SCHEMBL1312525 0.63 MMP13 (0.38) L3MBTL1
SCHEMBL16495171 0.63 ALDH1A1 (0.40) L3MBTL1
SCHEMBL1312913 0.63 ALDH1A1 (0.34) L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2292613-A1 DIHYDROINDOLINONE DERIVATIVES Shanghai Institute of Pharmaceutical Industry (CN) 2011-03-09 EP disclosed