Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 6/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13920479 | 0.85 | MIF (0.48) | CTSKPPARGPPARACTSSMAPT | |
| SCHEMBL31269578 | 0.84 | ALDH1A1 (0.44) | CTSKALDH1A1TSHRMAPK1TDP1 | |
| SCHEMBL13919630 | 0.84 | ITGB3 (0.43) | CTSKCTSSALDH1A1KDM4EMAPK1 | |
| SCHEMBL15952332 | 0.84 | TRPA1 (0.45) | CTSKPPARGPPARACTSSALDH1A1 | |
| SCHEMBL14847516 | 0.84 | TRPA1 (0.45) | CTSKPPARGPPARACTSSALDH1A1 | |
| SCHEMBL10154459 | 0.84 | NPC1 (0.49) | CTSKCTSSALDH1A1CACNA1BMEN1 | |
| SCHEMBL19348989 | 0.84 | CTSK (0.52) | CTSKPPARGPPARACTSSMAPT | |
| SCHEMBL10896010 | 0.84 | CTSK (0.52) | CTSKPPARGPPARACTSSMAPT | |
| SCHEMBL4715202 | 0.84 | CTSK (0.52) | CTSKPPARGPPARACTSSMAPT | |
| SCHEMBL30109141 | 0.83 | MAPT (0.50) | CTSKPPARGPPARACTSSMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008138561-A1 | TUBULYSINE DERIVATIVES | R & D BIOPHARMACEUTICALS GMBH (DE) | 2008-11-20 | — | — | WO | disclosed |