Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.50 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.48 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.44 |
| ▸ | ACHE | P22303 | 3/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14025022 | 0.87 | SLC7A5 (0.49) | SLC7A5TLR7CYP4F2CYP4A11SIGMAR1 | |
| SCHEMBL14437514 | 0.86 | SLC7A5 (0.48) | SLC7A5TLR7SIGMAR1ACHEBCHE | |
| SCHEMBL12400239 | 0.81 | SLC7A5 (0.68) | SLC7A5TLR7CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL15042327 | 0.79 | SLC7A5 (0.52) | SLC7A5TLR7CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL4577771 | 0.79 | ALDH1A1 (0.51) | ACHEBCHEALDH1A1 | |
| SCHEMBL8427611 | 0.79 | CYP4F2 (0.69) | SLC7A5TLR7CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL14025019 | 0.78 | SIGMAR1 (0.48) | SLC7A5TLR7SIGMAR1 | |
| SCHEMBL7718934 | 0.78 | SLC7A5 (0.60) | SLC7A5TLR7CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL335779 | 0.77 | SLC7A5 (0.59) | SLC7A5TLR7CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL4394735 | 0.76 | SLC7A5 (0.62) | SLC7A5TLR7CYP4F2CYP4A11ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080269240-A1 | Novel Adenine Compound | Dainippon Sumitomo Pharma Co., Ltd. a corporation of Japan (JP) | 2008-10-30 | — | — | US | disclosed |
| US-20080269240-A1 | Novel Adenine Compound | Dainippon Sumitomo Pharma Co., Ltd. a corporation of Japan (JP) | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269240-A1 | Novel Adenine Compound | ADORA1, ADORA2A, ADORA3 | SLC7A5 129/4885TLR7 612/4885CYP4F2 952/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.