Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | LGMN | Q99538 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19063266 | 0.85 | ALDH1A1 (0.46) | ALDH1A1MAPTKDM4EL3MBTL1ALOX15 | |
| SCHEMBL12733172 | 0.85 | GSK3B (0.47) | ACACBGSK3BALDH1A1MAPTKDM4E | |
| SCHEMBL14023935 | 0.83 | HRH3 (0.57) | ALDH1A1MAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL19062611 | 0.83 | ADRB1 (0.46) | ALDH1A1KDM4ELMNAHSD17B10USP2 | |
| SCHEMBL14025098 | 0.83 | ADRB1 (0.46) | ALDH1A1KDM4ELMNAHSD17B10USP2 | |
| SCHEMBL14025103 | 0.80 | KDM4E (0.45) | ALDH1A1KDM4EMEN1KMT2ACYP1A2 | |
| SCHEMBL27777300 | 0.80 | ALDH1A1 (0.51) | ACACBALDH1A1MAPTKDM4EL3MBTL1 | |
| SCHEMBL14023952 | 0.77 | DPP4 (0.36) | L3MBTL1 | |
| SCHEMBL14023957 | 0.77 | DPP4 (0.36) | L3MBTL1 | |
| SCHEMBL102286 | 0.76 | ALDH1A1 (0.58) | ACACBALDH1A1MAPTKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008143729-A2 | MACROLIDE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | RIB-X PHARMACEUTICALS, INC. (US) | 2008-11-27 | — | — | WO | disclosed |