SCHEMBL140260

SCHEMBL140260

CCCC(O)NC(O)CCC

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.36
HDAC7 Q8WUI4 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36
HDAC9 Q9UKV0 1/20 0.36
HDAC5 Q9UQL6 1/20 0.36
LMNA P02545 1/20 0.36
CHRM1 P11229 1/20 0.35
AKR1A1 P14550 1/20 0.35
CHRM3 P20309 1/20 0.35
HTR2A P28223 1/20 0.35
HTR2C P28335 1/20 0.35
ADRA1A P35348 1/20 0.35
HRH1 P35367 1/20 0.35
DRD3 P35462 1/20 0.35
SLC6A3 Q01959 1/20 0.35
HDAC1 Q13547 1/20 0.35
HDAC2 Q92769 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
CYP3A4 P08684 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29072198 0.91 LMNA (0.42) TSHRHDAC7HDAC8HDAC6HDAC9
SCHEMBL3160658 0.85
SCHEMBL2168975 0.85
Water SCHEMBL396092 0.83 TSHR (0.36) TSHRHDAC7HDAC8HDAC6HDAC9
SCHEMBL284650 0.81 ALDH1A1 (0.40) TSHRCYP3A4FDPS
SCHEMBL284731 0.79 GPR84 (0.44) LMNACYP3A4FDPS
SCHEMBL976563 0.78
SCHEMBL9358218 0.78
SCHEMBL13354313 0.77 TSHR (0.32) TSHR
SCHEMBL16618557 0.77 GPR84 (0.48) LMNACYP3A4FDPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1635 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12570535-B2 Method of manufacturing silica aerogel LG CHEM, LTD. (KR) 2026-03-10 US claimed
US-12550901-B2 Compositions containing glufosinate and a synthetic auxin herbicide CORTEVA AGRISCIENCE LLC (US) 2026-02-17 US claimed
EP-4628073-A1 COMPOSITION CONTAINING TRETINOIN, PREPARATION METHOD THEREFOR, AND USE THEREOF NANJING INDETEK LABORATORY CO., LTD. (CN) 2025-10-08 EP claimed
CN-119265639-B Preparation process of 6N high-purity nickel 光微半导体材料(宁波)有限公司 2025-06-03 CN claimed
CN-119140020-B Metal extractant microcapsule and preparation method thereof 光微半导体材料(宁波)有限公司 2025-06-03 CN claimed
CN-119925334-A Compound composition containing tranexamic acid and tretinoin 南京毓浠医药技术有限公司 2025-05-06 CN claimed
EP-4146588-B1 PROCESS FOR FUNCTIONALIZING A SURFACE OF A SOLID SUPPORT WITH NANO- OR MICROPARTICLES UNIV DE TECHNOLOGIE DE TROYES (FR) 2025-04-23 EP claimed
CN-119192526-A Polyurethane stock solution, low-density high-resilience polyurethane resin and application thereof 浙江华峰新材料有限公司 2024-12-27 CN claimed
CN-119118891-A Efficient metal chelating agent and preparation method and application thereof 光微半导体材料(宁波)有限公司 2024-12-13 CN claimed
CN-118290073-A Cement paste and application and well cementation method 中国石油化工股份有限公司 2024-07-05 CN claimed
US-5147730-A Multilayer; zinc,or alloy thereof, overcoated with chronmate, then dialkanolamine modified epoxy resin KAWASAKI STEEL CORP. (JP) 1992-09-15 US claimed
EP-0453677-A1 Depression of the flotation of silica or siliceous gangue in mineral flotation THE DOW CHEMICAL COMPANY (US) 1991-10-30 EP claimed
EP-0390122-A1 Steel plate with organic coating having improved corrosion resistance in as-worked state KAWASAKI STEEL CORPORATION (JP) 1990-10-03 EP claimed
EP-0385362-A1 Steel plate with organic coating having improved corrosion resistance KAWASAKI STEEL CORPORATION (JP) 1990-09-05 EP claimed
EP-0381377-A2 Improved corrosion preventive composition CASTROL INDUSTRIAL INC. (US) 1990-08-08 EP claimed
US-4927550-A FOR METAL WORKING CASTROL INDUSTRIAL INC. (US) 1990-05-22 US claimed
US-4796703-A REACTION PRODUCT OF SECONDARY AMINE AND GLYCERIDE IN CARRIER NALCO CHEMICAL COMPANY (US) 1989-01-10 US claimed
US-4683081-A Aqueous corrosion inhibitor compositions of a half-amide and a dicarboxylic acid amine salt FERRO CORPORATION (US) 1987-07-28 US claimed
US-4339367-A Modified cyclopentadiene resins, process for preparing the same, and a composition for printing ink containing said modified resins as vehicle component NIPPON ZEON CO., LTD. (JP) 1982-07-13 US claimed
US-3948909-A Ashless detergent dispersant for hydrocarbon oils TOA NENRYO KOGYO KABUSHIKI KAISHA (JA) 1976-04-06 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12550901-B2 Compositions containing glufosinate and a synthetic auxin herbicide GMNN, GRIN2D, GLUL TSHR 526/4885HDAC7 766/4885HDAC8 591/4885
US-12570535-B2 Method of manufacturing silica aerogel CFAP410, ATM, STIP1 TSHR 3093/4885HDAC7 4345/4885HDAC8 4425/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.