Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRHR | P34981 | 6/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4956855 | 0.94 | TRHR (0.66) | TRHR | |
| SCHEMBL17471543 | 0.88 | TRHR (0.71) | TRHR | |
| SCHEMBL9719678 | 0.88 | TRHR (0.71) | TRHR | |
| SCHEMBL11925276 | 0.87 | TRHR (0.70) | TRHR | |
| SCHEMBL8251476 | 0.83 | TRHR (0.51) | TRHR | |
| SCHEMBL10087854 | 0.81 | TRHR (0.61) | TRHR | |
| Protirelin SCHEMBL4406163 | 0.80 | TRHR (0.93) | TRHR | |
| Protirelin SCHEMBL33419 | 0.80 | TRHR (1.00) | TRHR | |
| Protirelin SCHEMBL10087855 | 0.80 | TRHR (1.00) | TRHR | |
| Protirelin SCHEMBL16091769 | 0.80 | TRHR (1.00) | TRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080249028-A1 | Thyrotropin-Releasing Hormone Analogs and Method of Use | ROGER WILLIAMS HOSPITAL (US) | 2008-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249028-A1 | Thyrotropin-Releasing Hormone Analogs and Method of Use | TRHR, IAPP, TRHDE | TRHR 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.