Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRHR | P34981 | 6/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17471543 | 1.00 | TRHR (0.71) | TRHR | |
| SCHEMBL11925276 | 0.91 | TRHR (0.70) | TRHR | |
| SCHEMBL14028672 | 0.88 | TRHR (0.66) | TRHR | |
| SCHEMBL4956855 | 0.86 | TRHR (0.66) | TRHR | |
| SCHEMBL10087854 | 0.85 | TRHR (0.61) | TRHR | |
| SCHEMBL11929118 | 0.84 | TRHR (0.92) | TRHR | |
| Protirelin SCHEMBL33419 | 0.83 | TRHR (1.00) | TRHR | |
| Protirelin SCHEMBL16091769 | 0.83 | TRHR (1.00) | TRHR | |
| Protirelin SCHEMBL10087855 | 0.83 | TRHR (1.00) | TRHR | |
| Protirelin SCHEMBL10087946 | 0.83 | TRHR (1.00) | TRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0373904-A1 | Process and composition for increasing brain dopamine release | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1990-06-20 | — | — | EP | claimed |
| US-5118670-A | PROCESS AND COMPOSITION FOR INCREASING BRAIN DOPAMINE RELEASE | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1992-06-02 | — | — | US | disclosed |
| EP-0373904-A1 | Process and composition for increasing brain dopamine release | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1990-06-20 | — | — | EP | disclosed |