SCHEMBL17471543

SCHEMBL17471543

Cn1cncc1CC(NC(=O)C1CCC(=O)N1)C(=O)N1CCCC1C(N)=O

nearest known ligand 0.71

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ TRHR P34981 6/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9719678 1.00 TRHR (0.71) TRHR
SCHEMBL11925276 0.91 TRHR (0.70) TRHR
SCHEMBL14028672 0.88 TRHR (0.66) TRHR
SCHEMBL4956855 0.86 TRHR (0.66) TRHR
SCHEMBL10087854 0.85 TRHR (0.61) TRHR
SCHEMBL11929118 0.84 TRHR (0.92) TRHR
Protirelin SCHEMBL33419 0.83 TRHR (1.00) TRHR
Protirelin SCHEMBL16091769 0.83 TRHR (1.00) TRHR
Protirelin SCHEMBL10087855 0.83 TRHR (1.00) TRHR
Protirelin SCHEMBL10087946 0.83 TRHR (1.00) TRHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3818070-B1 SYNTHETIC PEPTIDES, PRODRUGS, PHARMACEUTICAL COMPOSITIONS AND USES BIOZEUS DESENVOLVIMENTO DE PRODUTOS BIOFARMACEUTICOS (BR) 2026-03-11 — — EP disclosed
CN-112654634-B Synthetic peptides, prodrugs, pharmaceutical compositions and uses 生物医药产品开发公司 2022-05-27 — — CN disclosed
US-20180194732-A1 MULTI-API LOADING PRODRUGS JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT 2018-07-12 — — US disclosed
US-20160024011-A1 Multi-API Loading Prodrugs ALKERMES PHARMA IRELAND LTD (IE) 2016-01-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160024011-A1 Multi-API Loading Prodrugs AADAC, PAICS, ABCG2 TRHR 3350/4885
US-20180194732-A1 MULTI-API LOADING PRODRUGS AADAC, PAICS, ABCG2 TRHR 3350/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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