Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 8/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4950301 | 0.86 | LMNA (0.42) | WDR5ALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL463267 | 0.84 | WDR5 (0.52) | WDR5ALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL4951689 | 0.83 | WDR5 (0.38) | WDR5ALDH1A1NPC1RAB9ALMNA | |
| Acetic Acid SCHEMBL4952218 | 0.83 | ITGB3 (0.41) | WDR5ALDH1A1NPC1RAB9ALMNA | |
| Hydrochloric Acid SCHEMBL440262 | 0.83 | WDR5 (0.51) | WDR5ALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL407431 | 0.79 | WDR5 (0.47) | WDR5ALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL14305141 | 0.77 | WDR5 (0.45) | WDR5ALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL5311345 | 0.70 | WDR5 (0.41) | WDR5ALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL989261 | 0.67 | WDR5 (1.00) | WDR5ALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL4839937 | 0.66 | WDR5 (0.90) | WDR5ALDH1A1NPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7432278-B2 | Dicationic imidazo[1,2-a]pyridines and 5,6,7,8-tetrahydro-imidazo[1,2-a]pyridines as antiprotozoal agents | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2008-10-07 | — | — | US | disclosed |
| US-7432278-B2 | Dicationic imidazo[1,2-a]pyridines and 5,6,7,8-tetrahydro-imidazo[1,2-a]pyridines as antiprotozoal agents | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2008-10-07 | — | — | US | disclosed |