Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.45 |
| ▸ | NEK2 | P51955 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.40 |
| ▸ | VCP | P55072 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL440262 | 0.99 | WDR5 (0.51) | WDR5ALDH1A1NPC1LMNAHTT | |
| SCHEMBL407431 | 0.86 | WDR5 (0.47) | WDR5ALDH1A1NPC1LMNAHTT | |
| SCHEMBL14028700 | 0.84 | WDR5 (0.50) | WDR5ALDH1A1NPC1LMNAHTT | |
| SCHEMBL408909 | 0.78 | WDR5 (0.52) | WDR5ALDH1A1NPC1LMNAHTT | |
| Hydrochloric Acid SCHEMBL441011 | 0.77 | WDR5 (0.51) | WDR5ALDH1A1NPC1LMNAHTT | |
| SCHEMBL25170463 | 0.77 | KDM4E (0.43) | ALDH1A1KDM4EP2RX7NOTUMADORA3 | |
| SCHEMBL408206 | 0.74 | P2RX7 (0.36) | ALDH1A1KDM4EP2RX7NOTUMMEN1 | |
| SCHEMBL408891 | 0.71 | NOTUM (0.42) | NPC1RAB9AKDM4ENOTUMMAPT | |
| SCHEMBL4950301 | 0.70 | LMNA (0.42) | WDR5ALDH1A1NPC1LMNAHTT | |
| SCHEMBL989261 | 0.69 | WDR5 (1.00) | WDR5ALDH1A1NPC1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065196-A1 | AMIDE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065196-A1 | AMIDE COMPOUNDS | DGAT2, DGAT1, DLAT | WDR5 3363/4885ALDH1A1 272/4885NPC1 142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.