Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 6/20 | 0.53 |
| ▸ | TP53 | P04637 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14030931 | 0.76 | HTT (0.53) | HTTTP53LMNAMAPK1KDM4C | |
| SCHEMBL5037164 | 0.76 | HTT (0.60) | HTTTP53LMNAMAPK1KDM4C | |
| SCHEMBL14030971 | 0.75 | NPC1 (0.59) | HTTTP53LMNAMAPK1CA1 | |
| SCHEMBL5037127 | 0.75 | HTT (0.58) | HTTTP53LMNAMAPK1KDM4C | |
| SCHEMBL23242573 | 0.70 | TP53 (0.58) | HTTTP53LMNAMAPK1TDP1 | |
| SCHEMBL29800913 | 0.70 | TP53 (0.58) | HTTTP53LMNAMAPK1TDP1 | |
| SCHEMBL10027976 | 0.69 | LMNA (0.59) | HTTTP53LMNAMAPK1TDP1 | |
| SCHEMBL14030930 | 0.67 | HDAC3 (0.48) | LMNAGAAMAPTKMT2AMEN1 | |
| SCHEMBL13153595 | 0.66 | NPC1 (0.51) | HTTTP53LMNAMAPK1KDM4C | |
| SCHEMBL13233255 | 0.65 | RAB9A (0.56) | HTTTP53LMNAMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7439005-B2 | Styrene derivative, styrene polymer, photosensitive resin composition, and method for forming pattern | NEC CORPORATION (JP) | 2008-10-21 | — | — | US | disclosed |
| US-20070134586-A1 | Styrene derivative, styrene polymer, photosensitive resin composition, and method for forming pattern | NEC CORPORATION (JP) | 2007-06-14 | — | — | US | disclosed |