Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.48 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.46 |
| ▸ | PPM1D | O15297 | 2/20 | 0.46 |
| ▸ | MEP1B | Q16820 | 9/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL791813 | 0.84 | THRB (0.51) | KDM1APPM1DMEP1BNR1H4FOLH1 | |
| SCHEMBL21088517 | 0.84 | PPM1D (0.57) | KDM1APPM1DMEP1BALDH1A1EPHX1 | |
| SCHEMBL30444177 | 0.82 | KDM1A (0.54) | KDM1APPM1DMEP1BMAOAMAOB | |
| SCHEMBL14325231 | 0.81 | GRIN2B (0.51) | ALDH1A1 | |
| SCHEMBL13476626 | 0.77 | ALDH1A1 (0.43) | ALDH1A1FOLH1 | |
| SCHEMBL15830232 | 0.76 | PRMT5 (0.51) | KDM1APPM1DMEP1BMAOAMAOB | |
| SCHEMBL30443983 | 0.76 | KDM1A (0.51) | KDM1APPM1DMEP1BMAOAMAOB | |
| SCHEMBL18069755 | 0.75 | MEN1 (0.45) | ALDH1A1 | |
| SCHEMBL12510444 | 0.74 | PKM (0.62) | ALDH1A1EPHX1 | |
| SCHEMBL9057020 | 0.74 | POLB (0.54) | KDM1APPM1DALDH1A1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7439258-B2 | Viral polymerase inhibitors | BOEHRINGER INGELHEIM (CANADA) LTD (CA) | 2008-10-21 | — | — | US | disclosed |