Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7658469 | 0.86 | TSHR (0.53) | CYP2A6TSHRHSD17B10LOXL2CYP19A1 | |
| SCHEMBL29038971 | 0.85 | CYP2A6 (0.50) | CYP2A6TSHRHSD17B10LOXL2MAOB | |
| SCHEMBL19407082 | 0.81 | CYP2A6 (0.53) | CYP2A6TSHRHSD17B10HRH3LOXL2 | |
| SCHEMBL2201240 | 0.79 | RORC (0.53) | CYP2A6TSHRHSD17B10HRH3RORC | |
| SCHEMBL21396259 | 0.77 | TSHR (0.53) | CYP2A6TSHRHSD17B10HRH3LOXL2 | |
| SCHEMBL10091330 | 0.77 | TSHR (0.53) | CYP2A6TSHRHSD17B10HRH3LOXL2 | |
| SCHEMBL1637428 | 0.75 | SIGMAR1 (0.48) | CYP2A6TSHRHSD17B10HRH3RORC | |
| SCHEMBL10441823 | 0.74 | CYP2A6 (0.57) | CYP2A6TSHRHSD17B10HRH3LOXL2 | |
| Hydrochloric Acid SCHEMBL2205187 | 0.74 | SIGMAR1 (0.47) | CYP2A6TSHRHSD17B10HRH3RORC | |
| SCHEMBL5728985 | 0.73 | CYP2A6 (0.47) | CYP2A6TSHRHSD17B10HRH3LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080293951-A1 | Amin Derivative, and Production Method and Use Thereof | KUREHA CORPORATION | 2008-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293951-A1 | Amin Derivative, and Production Method and Use Thereof | BCAT2, BCAT1, MRPL9 | CYP2A6 436/4885TSHR 2682/4885HSD17B10 411/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.