Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.32 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | UBE2M | P61081 | 5/20 | 0.32 |
| ▸ | DCUN1D1 | Q96GG9 | 5/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14036542 | 0.93 | UBE2M (0.36) | TACR1RAB9AKCNK3KCNK9UBE2M | |
| SCHEMBL14036556 | 0.90 | UBE2M (0.40) | UBE2MDCUN1D1TP53 | |
| SCHEMBL14036567 | 0.88 | TACR1 (0.35) | TACR1TP53LMNAKDM4EALDH1A1 | |
| SCHEMBL14036562 | 0.85 | KMT2A (0.39) | RAB9ALMNAMAPK1SMN1; SMN2 | |
| SCHEMBL14036789 | 0.81 | PTPN1 (0.41) | LMNAMAPK1 | |
| SCHEMBL14036571 | 0.77 | TP53 (0.41) | UBE2MDCUN1D1TP53KDM4EALDH1A1 | |
| SCHEMBL14036548 | 0.76 | UBE2M (0.43) | UBE2MDCUN1D1TP53LMNASMN1; SMN2 | |
| SCHEMBL14036545 | 0.75 | LMNA (0.36) | UBE2MDCUN1D1TP53LMNAKDM4E | |
| SCHEMBL14036558 | 0.75 | KMT2A (0.37) | RAB9ASMN1; SMN2 | |
| SCHEMBL14036575 | 0.74 | DDX3X (0.40) | TACR1RAB9AAAK1LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008137102-A2 | METHODS OF MODULATING AMYLOID BETA AND COMPOUNDS USEFUL THEREFOR | TORREYPINES THERAPEUTICS, INC. (US) | 2008-11-13 | — | — | WO | disclosed |