Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NAMPT | P43490 | 4/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14036562 | 0.90 | KMT2A (0.39) | KMT2AMEN1HTTMAPTNAMPT | |
| SCHEMBL14036789 | 0.85 | PTPN1 (0.41) | KMT2AMEN1HTTMAPTPTPN1 | |
| SCHEMBL14036557 | 0.76 | NPC1 (0.47) | KMT2AMEN1HTTMAPTNAMPT | |
| SCHEMBL14036555 | 0.75 | TACR1 (0.33) | RAB9ASMN1; SMN2 | |
| SCHEMBL14036542 | 0.73 | UBE2M (0.36) | HTTMAPTRAB9A | |
| SCHEMBL14036556 | 0.73 | UBE2M (0.40) | MAPTROCK2 | |
| SCHEMBL14036546 | 0.70 | NPC1 (0.52) | KMT2AMEN1HTTMAPTNAMPT | |
| SCHEMBL14036690 | 0.67 | GAA (0.43) | KMT2AMEN1HTTMAPTSMN1; SMN2 | |
| SCHEMBL14036621 | 0.63 | MEN1 (0.49) | KMT2AMEN1HTTMAPTSMN1; SMN2 | |
| SCHEMBL5013641 | 0.63 | POLB (0.43) | KMT2AMEN1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008137102-A2 | METHODS OF MODULATING AMYLOID BETA AND COMPOUNDS USEFUL THEREFOR | TORREYPINES THERAPEUTICS, INC. (US) | 2008-11-13 | — | — | WO | disclosed |