Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.47 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.37 |
| ▸ | TYR | P14679 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5281640 | 0.89 | TAAR1 (0.50) | TAAR1RIPK1GPR52IDO1TYR | |
| SCHEMBL28323431 | 0.86 | ADRB2 (0.41) | ADRB2ADRB1TYRTSHR | |
| SCHEMBL8713115 | 0.80 | LTB4R (0.48) | TAAR1GPR52TSHRHPGD | |
| SCHEMBL28957063 | 0.79 | MPO (0.49) | TAAR1TYRTSHR | |
| SCHEMBL15255040 | 0.79 | TAAR1 (0.48) | TAAR1ADRB2ADRB1TYRTSHR | |
| SCHEMBL15532115 | 0.78 | TAAR1 (0.47) | TAAR1RIPK1GPR52IDO1TSHR | |
| SCHEMBL14997308 | 0.76 | TAAR1 (0.44) | TAAR1RIPK1IDO1TSHRHPGD | |
| SCHEMBL29679614 | 0.76 | TAAR1 (0.44) | TAAR1RIPK1IDO1TSHRHPGD | |
| SCHEMBL625240 | 0.76 | TAAR1 (0.44) | TAAR1RIPK1IDO1TSHRHPGD | |
| SCHEMBL4365156 | 0.76 | TAAR1 (0.54) | TAAR1GPR52IDO1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2834233-A1 | NEW ALPHA2 ADRENOCEPTOR AGONISTS | Orion Corporation (FI) | 2015-02-11 | — | — | EP | disclosed |
| WO-2013150173-A1 | NEW ALPHA2 ADRENOCEPTOR AGONISTS | ORION CORPORATION (FI) | 2013-10-10 | — | — | WO | disclosed |
| WO-2008135826-A2 | 2 -PYRIDINE CARBOXAMIDE DERIVATIVES AS SODIUM CHANNEL MODULATORS | PFIZER LIMITED (GB) | 2008-11-13 | — | — | WO | disclosed |