Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.50 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.50 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 6/20 | 0.38 |
| ▸ | BCHE | P06276 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | PLG | P00747 | 2/20 | 0.35 |
| ▸ | KLK1 | P06870 | 2/20 | 0.35 |
| ▸ | KLK6 | Q92876 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18181434 | 0.84 | TAAR1 (0.60) | LMNAPTGS1TRPA1CACNA1CHTR1D | |
| SCHEMBL17119507 | 0.83 | LMNA (0.47) | LMNAPTGS1TRPA1CACNA1CHTR1D | |
| SCHEMBL11449732 | 0.81 | LMNA (0.54) | LMNAPTGS1TRPA1CACNA1CHTT | |
| SCHEMBL13452414 | 0.80 | TAAR1 (0.34) | LMNAPTGS1TRPA1CACNA1CALDH1A1 | |
| SCHEMBL14227856 | 0.79 | LMNA (0.52) | LMNAPTGS1TRPA1CACNA1CHTT | |
| SCHEMBL12535558 | 0.79 | LMNA (0.52) | LMNAPTGS1TRPA1CACNA1CHTT | |
| SCHEMBL26137536 | 0.79 | HTR1D (0.40) | LMNAPTGS1TRPA1CACNA1CHTR1D | |
| SCHEMBL1762784 | 0.79 | LMNA (0.52) | LMNAPTGS1TRPA1CACNA1CHTT | |
| SCHEMBL20835018 | 0.79 | ALDH1A1 (0.48) | LMNAPTGS1TRPA1CACNA1CHTR1D | |
| SCHEMBL9685093 | 0.79 | PTGS1 (0.55) | LMNAPTGS1TRPA1CACNA1CHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11696903-B2 | Compounds and methods for scavenging dicarbonyl electrophiles | VANDERBILT UNIVERSITY (US) | 2023-07-11 | — | — | US | disclosed |
| US-20150265584-A1 | LEVUGLANDIN ADDUCTS HISTONE H4 IN A CYCLOOXYGENASE-2-DEPENDENT MANNER, ALTERING ITS INTERACTION WITH DNA | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2015-09-24 | — | — | US | disclosed |
| WO-2008137102-A2 | METHODS OF MODULATING AMYLOID BETA AND COMPOUNDS USEFUL THEREFOR | TORREYPINES THERAPEUTICS, INC. (US) | 2008-11-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150265584-A1 | LEVUGLANDIN ADDUCTS HISTONE H4 IN A CYCLOOXYGENASE-2-DEPENDENT MANNER, ALTERING ITS INTERACTION WITH DNA | H1-2, H1-4, H1-3 | LMNA 174/4885PTGS1 9/4885TRPA1 1983/4885 |
| US-11696903-B2 | Compounds and methods for scavenging dicarbonyl electrophiles | OGG1, LGMN, GLO1 | LMNA 51/4885PTGS1 157/4885TRPA1 1725/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.