Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 5/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 7/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | GLS | O94925 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5017051 | 0.81 | HTR2C (0.38) | CACNA1GCACNA1BCACNA1CHTR2CSLC6A4 | |
| SCHEMBL31163069 | 0.79 | POLB (0.42) | CACNA1GCACNA1BCACNA1CHTR2CSLC6A4 | |
| SCHEMBL20054017 | 0.79 | POLB (0.42) | CACNA1GCACNA1BCACNA1CHTR2CSLC6A4 | |
| SCHEMBL25211795 | 0.78 | PYCR1 (0.46) | CACNA1GCACNA1BCACNA1CHTR2CSLC6A4 | |
| SCHEMBL30264826 | 0.78 | HSP90AA1 (0.47) | HTR2CSLC6A4RIPK1GLSPDK2 | |
| SCHEMBL12231498 | 0.77 | HTR2C (0.39) | CACNA1GCACNA1BCACNA1CHTR2CSLC6A4 | |
| SCHEMBL5015044 | 0.77 | ACHE (0.42) | CACNA1GCACNA1BCACNA1CHTR2CSLC6A4 | |
| SCHEMBL8017533 | 0.77 | HTR2C (0.47) | CACNA1GCACNA1BCACNA1CHTR2CSLC6A4 | |
| SCHEMBL5013658 | 0.76 | CACNA1G (0.36) | CACNA1GCACNA1BCACNA1CHTR2CSLC6A4 | |
| SCHEMBL1831753 | 0.75 | ALDH1A1 (0.41) | HTR2CSLC6A4MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008137102-A2 | METHODS OF MODULATING AMYLOID BETA AND COMPOUNDS USEFUL THEREFOR | TORREYPINES THERAPEUTICS, INC. (US) | 2008-11-13 | — | — | WO | disclosed |