Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 5/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14036774 | 0.85 | GAA (0.51) | SLC6A4SLC6A2SLC6A3ALDH1A1TSHR | |
| SCHEMBL10145745 | 0.82 | NPBWR1 (0.42) | ALDH1A1TSHRLMNAHSD17B10GAA | |
| SCHEMBL2625747 | 0.79 | LMNA (0.47) | ALDH1A1TSHRLMNAHSD17B10GAA | |
| SCHEMBL7887194 | 0.77 | LMNA (0.40) | ALDH1A1TSHRLMNAHSD17B10GAA | |
| Dimethylamine SCHEMBL11221773 | 0.75 | ADRA1D (0.44) | ALDH1A1TSHRLMNAHSD17B10GAA | |
| SCHEMBL21652642 | 0.75 | SLC6A4 (0.37) | SLC6A4SLC6A2SLC6A3HTR2AKCNH2 | |
| SCHEMBL5015048 | 0.73 | SLC6A4 (0.36) | SLC6A4SLC6A2SLC6A3HTR2AKCNH2 | |
| SCHEMBL12051647 | 0.73 | ALDH1A1 (0.49) | ALDH1A1TSHRLMNAHSD17B10GAA | |
| SCHEMBL7896143 | 0.73 | TRPV1 (0.41) | ALDH1A1TSHRNPSR1 | |
| SCHEMBL12129212 | 0.73 | TSHR (0.52) | ALDH1A1TSHRLMNAHSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008137102-A2 | METHODS OF MODULATING AMYLOID BETA AND COMPOUNDS USEFUL THEREFOR | TORREYPINES THERAPEUTICS, INC. (US) | 2008-11-13 | — | — | WO | disclosed |