Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28767120 | 0.83 | LMNA (0.57) | LMNAADRA1DADRA1AADRA1BCYP1A2 | |
| SCHEMBL11132329 | 0.81 | CYP1A2 (0.61) | LMNAADRA1DADRA1AADRA1BCYP1A2 | |
| SCHEMBL29498877 | 0.80 | LMNA (0.55) | LMNAADRA1DADRA1AADRA1BCYP1A2 | |
| SCHEMBL22235472 | 0.80 | LMNA (0.55) | LMNAADRA1DADRA1AADRA1BCYP1A2 | |
| SCHEMBL14036788 | 0.77 | ADRA1D (0.41) | LMNAADRA1DADRA1AADRA1BCYP1A2 | |
| SCHEMBL14036622 | 0.75 | POLB (0.65) | LMNASMN1; SMN2POLBGAAGFER | |
| SCHEMBL11134803 | 0.75 | LMNA (0.44) | LMNAADRA1DADRA1AADRA1BCYP1A2 | |
| SCHEMBL9500070 | 0.73 | ALDH1A1 (0.57) | SMN1; SMN2POLBMAPTTSHRMAPK1 | |
| SCHEMBL14036780 | 0.73 | KDM4E (0.36) | LMNAADRA1DADRA1AADRA1BCYP1A2 | |
| SCHEMBL5529615 | 0.70 | LMNA (0.45) | LMNAADRA1DADRA1AADRA1BCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008137102-A2 | METHODS OF MODULATING AMYLOID BETA AND COMPOUNDS USEFUL THEREFOR | TORREYPINES THERAPEUTICS, INC. (US) | 2008-11-13 | — | — | WO | disclosed |