Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 4/20 | 0.46 |
| ▸ | MMP9 | P14780 | 4/20 | 0.46 |
| ▸ | MMP8 | P22894 | 4/20 | 0.46 |
| ▸ | MMP13 | P45452 | 4/20 | 0.46 |
| ▸ | PSMD10 | O75832 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 5/20 | 0.37 |
| ▸ | CA2 | P00918 | 5/20 | 0.37 |
| ▸ | CA9 | Q16790 | 5/20 | 0.37 |
| ▸ | CA12 | O43570 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.34 |
| ▸ | TUBB | P07437 | 1/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL943760 | 0.88 | CA12 (0.51) | MMP2MMP9MMP8MMP13PSMD10 | |
| SCHEMBL14043067 | 0.78 | MAPK1 (0.42) | CA1CA2CA9CA12MAPK1 | |
| SCHEMBL14925314 | 0.75 | MMP2 (0.51) | MMP2MMP9MMP8MMP13PSMD10 | |
| SCHEMBL941807 | 0.74 | MMP2 (0.43) | MMP2MMP9MMP8MMP13PSMD10 | |
| SCHEMBL14924261 | 0.73 | MMP2 (0.49) | MMP2MMP9MMP8MMP13PSMD10 | |
| SCHEMBL8211578 | 0.68 | ALDH1A1 (0.44) | PSMD10CA1CA2CA9CA12 | |
| SCHEMBL16511356 | 0.67 | PSMD10 (0.51) | MMP2MMP9MMP8MMP13PSMD10 | |
| SCHEMBL941683 | 0.66 | LMNA (0.61) | CA1CA2CA9CA12KMT2A | |
| SCHEMBL16510904 | 0.66 | PSMD10 (0.49) | MMP2MMP9MMP8MMP13PSMD10 | |
| SCHEMBL13104167 | 0.66 | CYP3A4 (0.56) | CA1CA2CA9CA12KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008124651-A2 | NITRO-IMIDAZOLE HYPOXIA IMAGING AGENTS | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2008-10-16 | — | — | WO | disclosed |