Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.32 |
| ▸ | LOX | P28300 | 1/20 | 0.32 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8738571 | 0.82 | ALDH1A1 (0.35) | TNKS2GAACYP2A6 | |
| SCHEMBL18885163 | 0.82 | TNKS2 (0.34) | TNKS2 | |
| SCHEMBL13354838 | 0.78 | LMNA (0.34) | TNKS2 | |
| SCHEMBL2194416 | 0.76 | KDM4E (0.32) | GAA | |
| SCHEMBL19139944 | 0.72 | TP53 (0.41) | TNKS2 | |
| SCHEMBL30695309 | 0.72 | HTR5A (0.33) | — | |
| SCHEMBL1257327 | 0.72 | AHR (0.35) | — | |
| SCHEMBL5333036 | 0.72 | TGM2 (0.32) | — | |
| SCHEMBL8469855 | 0.72 | ALDH1A1 (0.34) | GAACYP2A6 | |
| SCHEMBL9453911 | 0.72 | DRD2 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008130570-A1 | NOVEL PYRAZOLOPYRIMIDINES AS CYCLIN DEPENDENT KINASE INHIBITORS | SCHERING CORPORATION (US) | 2008-10-30 | — | — | WO | disclosed |