Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MPO | P05164 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13683095 | 0.83 | CA1 (0.38) | MPOPOLB | |
| SCHEMBL16200192 | 0.80 | IDO1 (0.36) | ALDH1A1L3MBTL1 | |
| SCHEMBL16200162 | 0.77 | ALDH1A1 (0.33) | ALDH1A1L3MBTL1 | |
| SCHEMBL14139219 | 0.77 | — | — | |
| SCHEMBL16200177 | 0.66 | CA1 (0.43) | ALDH1A1L3MBTL1POLB | |
| SCHEMBL16200156 | 0.62 | RECQL (0.38) | — | |
| SCHEMBL6112453 | 0.61 | POLB (0.47) | MPOPOLB | |
| SCHEMBL19738062 | 0.61 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1 | |
| SCHEMBL13683155 | 0.60 | ADCY10 (0.36) | — | |
| SCHEMBL14044161 | 0.60 | HDAC3 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7435830-B2 | Bicyclic and bridged nitrogen heterocycles | CHEMOCENTRYX, INC. (US) | 2008-10-14 | — | — | US | disclosed |