SCHEMBL472542

SCHEMBL472542

O=c1c2ccccc2sc2ccc([N+](=O)[O-])cc12

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.57
CTSV O60911 1/20 0.55
CTSL P07711 1/20 0.55
MAPT P10636 6/20 0.53
ALDH1A1 P00352 4/20 0.53
RAB9A P51151 2/20 0.53
NPC1 O15118 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
PARP1 P09874 1/20 0.51
SMN1; SMN2 Q16637 3/20 0.51
POLB P06746 1/20 0.51
G6PD P11413 1/20 0.50
TLR9 Q9NR96 1/20 0.50
MAOA P21397 1/20 0.45
MAOB P27338 1/20 0.45
S100A4 P26447 1/20 0.45
KMT2A Q03164 3/20 0.45
MEN1 O00255 2/20 0.45
PSMD14 O00487 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29724161 1.00 KDM4E (0.57) KDM4ECTSVCTSLMAPTALDH1A1
SCHEMBL8086574 0.90 CTSV (0.51) KDM4ECTSVCTSLMAPTALDH1A1
SCHEMBL5115377 0.88 PARP1 (0.51) KDM4ECTSVCTSLMAPTALDH1A1
Ethane SCHEMBL27503799 0.88 CTSV (0.49) KDM4ECTSVCTSLMAPTALDH1A1
Methane SCHEMBL27594830 0.87 MAPT (0.50) KDM4ECTSVCTSLMAPTALDH1A1
Bicarbonate SCHEMBL11113604 0.85 PHOSPHO1 (0.49) KDM4ECTSVCTSLMAPTALDH1A1
SCHEMBL15227310 0.83 MAPT (0.54) CTSVCTSLMAPTALDH1A1RAB9A
SCHEMBL11160019 0.83 MAPT (0.54) CTSVCTSLMAPTALDH1A1TDP1
SCHEMBL11118149 0.82 SMN1; SMN2 (0.50) MAPTALDH1A1TDP1PARP1SMN1; SMN2
SCHEMBL16857506 0.82 EGFR (0.50) KDM4ECTSVCTSLMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 343 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8367745-B2 Includes alkaline earth metal oxide as acidity neutralization stabilizer; quick setting, mechanical strength; repairing prosthesis GC CORPORATION (JP) 2013-02-05 US claimed
US-7678843-B2 Dental restorative material composition GC CORPORATION (JP) 2010-03-16 US claimed
US-5770638-A CONSISTS OF TETRAHYDROFURFURYL METHACRYLATE, ONE OR MORE METHACRYLATE HAVING ATLEAST ONE DOUBLE BOND SELECTED FROM DI-2-METHACRYLOXYETHYL-2,2-4-TRIMETHYLHEXAMETHYLENE DICARBAMATE AND OTHER ACRYLATED CARBAMATE AND PHOTOINITIATORS GC CORPORATION (JP) 1998-06-23 US claimed
EP-4029839-B1 GLASS POWDER AND CHEMICAL POLYMERIZATION INITIATOR G C DENTAL IND CORP (JP) 2026-05-06 EP disclosed
US-12600867-B2 Method of coating article, use for coating article, and polymerizable composition GC CORPORATION (JP) 2026-04-14 US disclosed
EP-3669854-B1 PHOTOPOLYMERIZABLE DENTAL COMPOSITION G C DENTAL IND CORP (JP) 2026-04-08 EP disclosed
EP-4514304-B1 DENTAL COMPOSITION CONTAINING A RESORCINOL OR CATECHOL MOIETY CONTAINING COMPONENT AND USE THEREOF SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2026-03-25 EP disclosed
US-12577340-B2 Storage stable two-component dual cure dental composition SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2026-03-17 US disclosed
US-12569409-B2 Dental polymerizable composition GC CORPORATION (JP) 2026-03-10 US disclosed
US-12497476-B2 Antibacterial polymer particles, composition, and article GC CORPORATION (JP) 2025-12-16 US disclosed
EP-4652982-A1 DENTAL RESTORATION MATERIAL COMPOSITION GC R&D Corporation (JP) 2025-11-26 EP disclosed
US-5356951-A (Meth)acrylate monomer; composite filler; glass powder; fine particle filler; photoinitiator; surface smoothness; less shrinkage GC CORPORATION (JP) 1994-10-18 US disclosed
US-5290172-A Method for preparing a tooth surface for bonding GC CORPORATION (JP) 1994-03-01 US disclosed
US-5254604-A Light polymerizable resin compositions for the preparation of clasp patterns G-C TOSHI KOGYO CORPORATION (JP) 1993-10-19 US disclosed
US-5063255-A (Meth)acrylates G-C TOSHI KOGYO CORPORATION (JP) 1991-11-05 US disclosed
US-4843110-A BLEND CONTAINING A THIOXANTHONE PHOTOINITIATOR G-C DENTAL INDUSTRIAL CORPORATION (JP) 1989-06-27 US disclosed
CN-85100270-A The photo-hardening method of siccative oil and resins derived therefrom thereof 1986-08-06 CN disclosed
US-4544467-A PHOSPHOROUS-CONTAINING UNSATURATED MONOMER , SULFUR COMPOUND AND PHOTOINITIATOR; BONDING STRENGTH MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-10-01 US disclosed
EP-0132318-A1 Light-curable dentin and enamel adhesive MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-01-30 EP disclosed
US-4379039-A Ultraviolet curable resin composition TOYO BOSEKI KABUSHIKI KAISH (JP) 1983-04-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12569409-B2 Dental polymerizable composition VCL, ACR, TPO KDM4E 2589/4885CTSV 4049/4885CTSL 4074/4885
US-12600867-B2 Method of coating article, use for coating article, and polymerizable composition SARS1, SPIN1, ESPL1 KDM4E 1434/4885CTSV 1181/4885CTSL 270/4885
US-12497476-B2 Antibacterial polymer particles, composition, and article PCNA, PARG, PUF60 KDM4E 3196/4885CTSV 2629/4885CTSL 2593/4885
US-12577340-B2 Storage stable two-component dual cure dental composition GPX4, SSRP1, H1-0 KDM4E 1053/4885CTSV 3876/4885CTSL 1280/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.