Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | KLRK1 | P26718 | 2/20 | 0.49 |
| ▸ | MICA | Q29983 | 2/20 | 0.49 |
| ▸ | RAET1L | Q5VY80 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.49 |
| ▸ | KCNA3 | P22001 | 3/20 | 0.47 |
| ▸ | CLPP | Q16740 | 2/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8696620 | 0.87 | CHRNB2 (0.59) | MEN1KMT2ACLPPCHRNB2CHRNB4 | |
| SCHEMBL6797969 | 0.83 | SLC6A3 (0.71) | MEN1KMT2ATSHRSLC6A3SLC6A4 | |
| SCHEMBL29978969 | 0.83 | SLC6A3 (0.71) | MEN1KMT2ATSHRSLC6A3SLC6A4 | |
| SCHEMBL14046203 | 0.82 | CDK4 (0.49) | MEN1KMT2AKLRK1MICARAET1L | |
| SCHEMBL9864612 | 0.82 | MEN1 (0.50) | MEN1KMT2AKLRK1MICARAET1L | |
| SCHEMBL4741406 | 0.80 | DHODH (0.56) | MEN1KMT2AUSP2LMNAMAPT | |
| SCHEMBL5937166 | 0.79 | SLC6A3 (0.49) | MEN1KMT2AKLRK1MICARAET1L | |
| Hydrochloric Acid SCHEMBL5937171 | 0.79 | DHODH (0.55) | MEN1KMT2AUSP2LMNAMAPT | |
| SCHEMBL2563193 | 0.79 | BCAT2 (0.65) | MEN1KMT2ATSHRSLC6A3SLC6A4 | |
| SCHEMBL14046209 | 0.78 | ALDH1A1 (0.42) | MEN1KMT2AKCNA3USP2MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080249130-A1 | Gut microsomal triglyceride transport protein inhibitors | SIRTRIS PHARMACEUTICALS, INC. (US) | 2008-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249130-A1 | Gut microsomal triglyceride transport protein inhibitors | MTTP, CETP, FABP2 | MEN1 3927/4885KMT2A 2256/4885KLRK1 3791/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.