Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.43 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.43 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.43 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.43 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.43 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.43 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.42 |
| ▸ | KLRK1 | P26718 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9864612 | 0.86 | MEN1 (0.50) | SLC6A3SLC6A4MEN1KMT2AUSP2 | |
| SCHEMBL4741406 | 0.84 | DHODH (0.56) | MEN1KMT2AUSP2LMNAMAPT | |
| Hydrochloric Acid SCHEMBL5937171 | 0.83 | DHODH (0.55) | MEN1KMT2AUSP2LMNAMAPT | |
| SCHEMBL2563193 | 0.83 | BCAT2 (0.65) | SLC6A3SLC6A4MEN1KMT2AUSP2 | |
| SCHEMBL28640320 | 0.82 | SLC6A3 (0.64) | SLC6A3SLC6A4MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1580001 | 0.80 | SLC6A3 (0.49) | SLC6A3SLC6A4MEN1KMT2ALMNA | |
| SCHEMBL30436191 | 0.80 | SLC6A3 (0.49) | SLC6A3SLC6A4MEN1KMT2ALMNA | |
| SCHEMBL6797969 | 0.80 | SLC6A3 (0.71) | SLC6A3SLC6A4MEN1KMT2AUSP2 | |
| SCHEMBL29978969 | 0.80 | SLC6A3 (0.71) | SLC6A3SLC6A4MEN1KMT2AUSP2 | |
| SCHEMBL18825620 | 0.80 | BCAT2 (0.59) | SLC6A3SLC6A4MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060058372-A1 | N-Benzodioxolyl, n-benzodioxanyl and n-benzodioxepinyl arylcarboxamide derivatives and pharmaceutical compositions comprising them | MERCK PATENT GMBH (DE) | 2006-03-16 | — | — | US | disclosed |
| EP-1554263-A1 | N-BENZODIOXOLYL, N-BENZODIOXANYL AND N-BENZODIOXEPINYL ARYLCARBONXAMIDE DERIVATIVES, AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | MERCK PATENT GmbH (DE) | 2005-07-20 | — | — | EP | disclosed |
| WO-2004037806-A1 | N-BENZODIOXOLYL, N-BENZODIOXANYL AND N-BENZODIOXEPINYL ARYLCARBONXAMIDE DERIVATIVES, AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | MERCK PATENT GMBH (DE) | 2004-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060058372-A1 | N-Benzodioxolyl, n-benzodioxanyl and n-benzodioxepinyl arylcarboxamide derivatives and pharmaceutical compositions comprising them | TBXAS1, PCSK9, APOB | SLC6A3 2917/4885SLC6A4 2127/4885MEN1 4449/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.